Products for Research Use Only
RegisterLogin

TFEB Antibody

CAT: 0247-OAAF02178-100UGSize: 100 µgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0247-OAAF02178-100UGSize:100 µg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
CAS Number
9007-83-4
Gene Name
Transcription factor EB
Gene Aliases
ALPHATFEB; BHLHE35; class E basic helix-loop-helix protein 35; T-cell transcription factor EB; TCFEB; transcription factor EB.
Gene ID
7942
Swiss Prot
P19484
Accession Number
NP_001161299.2
Reactivity
Human|Mouse
Immunogen
The antiserum was produced against synthesized peptide derived from human TFEB.
Target
Transcription factor that specifically recognizes and binds E-box sequences (5'-CANNTG-3') . Efficient DNA-binding requires dimerization with itself or with another MiT/TFE family member such as TFE3 or MITF. In association with TFE3, activates the expression of CD40L in T-cells, thereby playing a role in T-cell-dependent antibody responses in activated CD4 (+) T-cells and thymus-dependent humoral immunity. Specifically recognizes and binds the CLEAR-box sequence (5'-GTCACGTGAC-3') present in the regulatory region of many lysosomal genes, leading to activate their expression. It thereby plays a central role in expression of lysosomal genes. Acts as a positive regulator of autophagy by promoting expression of genes involved in autophagy. Specifically recognizes the gamma-E3 box, a subset of E-boxes, present in the heavy-chain immunoglobulin enhancer. Plays a role in the signal transduction processes required for normal vascularization of the placenta.
Clonality
Polyclonal
Type
Polyclonal Antibody
Applications
Enzyme-linked immunosorbent assay|Immunofluorescence|Immunohistochemistry|Immunohistochemistry-Paraffin|Western blot
Purification
The antibody was purified from rabbit antiserum by affinity-chromatography using immunogen.
Assay Protocol
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol
Concentration
1 mg/ml
Dilution
The optimal working dilution should be determined by the end user.
Format
Liquid.// PBS (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Reconstitution
-20°C
Molecular Weight
52 kDa
Notes
Formerly GWB-ASD434
Fragment
IgG
Specificity
TFEB antibody detects endogenous levels of total TFEB protein.
NCBI Gene Symbol
TFEB
Host or Source
Rabbit
Protein Name
Transcription factor EB
Gene Name URL
TFEB

Related Products

CatalogName
AAP38810-100UGTFEB Peptide (AAP38810)
OCOA11778-20UGTFEB Protein Lysate
AAP58116-100UGTFEB Peptide - middle region (AAP58116)
AAP72647-100UGTFEB Peptide - C-terminal region (AAP72647)
OAAJ04003-100ULTFE3 Antibody
OAAL00578-100UGTFEC Antibody
OAAJ01960-100ULTFE3 Antibody
OAEB01034-100UGTFE3 Antibody
OAEB01693-100UGTFEC Antibody
OAAF02179-100UGTFE3 Antibody

Alternative Products

CatalogName
70R-12852TFEB antibody

Popular Products