RECK Antibody

CAT: 0247-OAAF02091-100UGSize: 100 µgDry Ice: NoHazardous: No
CAT#:0247-OAAF02091-100UGSize:100 µg
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
9007-83-4
Gene Name
Reversion inducing cysteine rich protein with kazal motifs
Gene Aliases
Membrane-anchored glycoprotein (metastasis and invasion) ; reversion-inducing cysteine-rich protein with Kazal motifs; ST15; suppression of tumorigenicity 15 (reversion-inducing-cysteine-rich protein with kazal motifs) ; suppression of tumorigenicity 5 (reversion-inducing-cysteine-rich protein with kazal motifs) ; suppressor of tumorigenicity 15 protein.
Gene ID
8434
Swiss Prot
O95980
Accession Number
NP_066934.1
Reactivity
Human|Mouse
Immunogen
The antiserum was produced against synthesized peptide derived from human RECK.
Target
Negatively regulates matrix metalloproteinase-9 (MMP-9) by suppressing MMP-9 secretion and by direct inhibition of its enzymatic activity. RECK down-regulation by oncogenic signals may facilitate tumor invasion and metastasis. Appears to also regulate MMP-2 and MT1-MMP, which are involved in cancer progression.
Clonality
Polyclonal
Type
Polyclonal Antibody
Applications
Enzyme-linked immunosorbent assay|Immunocytochemistry|Immunofluorescence|Immunohistochemistry|Immunohistochemistry-Paraffin|Western blot
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Assay Protocol
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol
Dilution
The optimal working dilution should be determined by the end user.
Format
Liquid
Reconstitution
-20°C
Molecular Weight
106 kDa
Specificity
RECK antibody detects endogenous levels of total RECK protein.
NCBI Gene Symbol
RECK
Host or Source
Rabbit
Protein Name
Reversion-inducing cysteine-rich protein with Kazal motifs
Gene Name URL
RECK

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