Products for Research Use Only
RegisterLogin

MKI67 Antibody

CAT: 0247-OAAF01852-100UGSize: 100 µgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0247-OAAF01852-100UGSize:100 µg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
Click here to learn more about Aviva's By-Request Conjugation Service.//here
CAS Number
9007-83-4
Gene Name
Marker of proliferation Ki-67
Gene Aliases
Antigen identified by monoclonal antibody Ki-67; antigen Ki67; KIA; MIB-; MIB-1; Molecular Immunology Borstel antibody 1; PPP1R105; proliferation marker protein Ki-67; proliferation-related Ki-67 antigen; protein phosphatase 1, regulatory subunit 105.
Gene ID
4288
Swiss Prot
P46013
Accession Number
NP_001139438.1
Reactivity
Human|Mouse|Rat
Immunogen
The antiserum was produced against synthesized peptide derived from human Ki67.
Target
Required to maintain individual mitotic chromosomes dispersed in the cytoplasm following nuclear envelope disassembly (PubMed:27362226) . Associates with the surface of the mitotic chromosome, the perichromosomal layer, and covers a substantial fraction of the chromosome surface (PubMed:27362226) . Prevents chromosomes from collapsing into a single chromatin mass by forming a steric and electrostatic charge barrier: the protein has a high net electrical charge and acts as a surfactant, dispersing chromosomes and enabling independent chromosome motility (PubMed:27362226) . Binds DNA, with a preference for supercoiled DNA and AT-rich DNA (PubMed:10878551) . Does not contribute to the internal structure of mitotic chromosomes (By similarity) . May play a role in chromatin organization (PubMed:24867636) . It is however unclear whether it plays a direct role in chromatin organization or whether it is an indirect consequence of its function in maintaining mitotic chromosomes dispersed (Probable) .
Clonality
Polyclonal
Type
Polyclonal Antibody
Applications
Enzyme-linked immunosorbent assay|Immunocytochemistry|Immunofluorescence|Immunohistochemistry-Paraffin|Western blot
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Assay Protocol
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol
Dilution
The optimal working dilution should be determined by the end user.
Format
Liquid
Reconstitution
-20°C
Molecular Weight
358 kDa
Notes
Formerly GWB-ASD123
Specificity
Ki67 antibody detects endogenous levels of total ki67protein.
NCBI Gene Symbol
MKI67
Host or Source
Rabbit
Protein Name
Proliferation marker protein Ki-67
Gene Name URL
MKI67

Related Products

CatalogName
OPCD04655-200UGMKI67 Recombinant Protein
OPCA01725-1MGMKI67 Recombinant Protein
OPCA03188-100UGMKI67 Recombinant Protein
OPCD04656-200UGMKI67 Recombinant Protein
OPCD04658-50UGMKI67 Recombinant Protein
OPCD04656-50UGMKI67 Recombinant Protein
OPCD04657-200UGMKI67 Recombinant Protein
OPCA03188-20UGMKI67 Recombinant Protein
OPCD04658-10UGMKI67 Recombinant Protein
OPCD04657-10UGMKI67 Recombinant Protein

Alternative Products

CatalogName
MBS7116530-01MKI67 Antibody

Popular Products