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KRT14 Antibody

CAT: 0247-OAAF01841-100UGSize: 100 µgDry Ice: NoHazardous: No
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CAT#:0247-OAAF01841-100UGSize:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
9007-83-4
Gene Name
Keratin 14|keratin 16|keratin 17
Gene Aliases
39.1; CK14; CK16; CK-17; cytokeratin 14; cytokeratin 16; Cytokeratin-14; Cytokeratin-16; cytokeratin-17; EBS3; EBS4; FNEPPK; focal non-epidermolytic palmoplantar keratoderma; K14; K16; K17; K1CP; keratin 14, type I; keratin 16, type I; keratin 17, type I; keratin, type I cytoskeletal 14; keratin, type I cytoskeletal 16; keratin, type I cytoskeletal 17; Keratin-14; Keratin-16; KRT16A; NEPPK; NFJ; PC; PC1; PC2; PCHC1.
Gene ID
3861|3868|3872
Swiss Prot
P02533|P08779
Accession Number
NP_000517.2
Reactivity
Human|Mouse|Rat
Immunogen
The antiserum was produced against synthesized peptide derived from human Keratin 14.
Target
Epidermis-specific type I keratin that plays a key role in skin. Acts as a regulator of innate immunity in response to skin barrier breach: required for some inflammatory checkpoint for the skin barrier maintenance.|The nonhelical tail domain is involved in promoting KRT5-KRT14 filaments to self-organize into large bundles and enhances the mechanical properties involved in resilience of keratin intermediate filaments in vitro.
Clonality
Polyclonal
Type
Polyclonal Antibody
Applications
Enzyme-linked immunosorbent assay|Immunocytochemistry|Immunofluorescence|Immunohistochemistry|Immunohistochemistry-Paraffin|Western blot
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Assay Protocol
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol
Dilution
The optimal working dilution should be determined by the end user.
Format
Liquid
Reconstitution
-20°C
Molecular Weight
51 kDa
Notes
Formerly GWB-ASD112
Specificity
Keratin 14 antibody detects endogenous levels of total Keratin 14 protein.
NCBI Gene Symbol
KRT14|KRT16|KRT17
Host or Source
Rabbit
Protein Name
Keratin, type I cytoskeletal 14|Keratin, type I cytoskeletal 16
Gene Name URL
KRT14|KRT16|KRT17

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