Products for Research Use Only
RegisterLogin

RBL2 Antibody

CAT: 0247-OAAF00962-100UGSize: 100 µgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0247-OAAF00962-100UGSize:100 µg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
CAS Number
9007-83-4
Gene Name
RB transcriptional corepressor like 2
Gene Aliases
130 kDa retinoblastoma-associated protein; P130; PRB2; Rb2; RBR-2; retinoblastoma-like 2; retinoblastoma-like protein 2; retinoblastoma-related protein 2.
Gene ID
5934
Swiss Prot
Q08999
Accession Number
NP_005602.3
Reactivity
Human|Mouse|Rat
Immunogen
The antiserum was produced against synthesized peptide derived from human RBL2.
Target
Key regulator of entry into cell division. Directly involved in heterochromatin formation by maintaining overall chromatin structure and, in particular, that of constitutive heterochromatin by stabilizing histone methylation. Recruits and targets histone methyltransferases KMT5B and KMT5C, leading to epigenetic transcriptional repression. Controls histone H4 'Lys-20' trimethylation. Probably acts as a transcription repressor by recruiting chromatin-modifying enzymes to promoters. Potent inhibitor of E2F-mediated trans-activation, associates preferentially with E2F5. Binds to cyclins A and E. Binds to and may be involved in the transforming capacity of the adenovirus E1A protein. May act as a tumor suppressor.
Clonality
Polyclonal
Type
Polyclonal Antibody
Applications
Enzyme-linked immunosorbent assay|Immunocytochemistry|Immunofluorescence
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Assay Protocol
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol
Dilution
The optimal working dilution should be determined by the end user.
Format
Liquid
Reconstitution
-20°C
Molecular Weight
128 kDa
Notes
Formerly GWB-ASC371
Specificity
Rb-like-2 antibody detects endogenous levels of total Rb-like-2 protein
NCBI Gene Symbol
RBL2
Host or Source
Rabbit
Protein Name
Retinoblastoma-like protein 2
Gene Name URL
RBL2

Related Products

CatalogName
OCOA12525-20UGRBL2 Protein Lysate
OKEH07807-96WRBL2 ELISA Kit (Mouse)
OKEH07806-96WRBL2 ELISA Kit (Human)
OKEH07806RBL2 ELISA Kit (Human) (OKEH07806)
OKEH07807RBL2 ELISA Kit (Mouse) (OKEH07807)
AAP38642-100UGRBL2 Peptide - C-terminal region (AAP38642)
AAP31026-100UGRBL2 Peptide - C-terminal region (AAP31026)
OAEG00075-100UGRBL1 Antibody
OAAB19757-100ULRBL1 Antibody
OAAF00961-100UGRBL1 Antibody

Alternative Products

CatalogName
70R-33427RBL2 antibody

Popular Products