ESPL1 Antibody

• Gene Name:

  Extra spindle pole bodies like 1, separase

• Gene Aliases:

  Caspase-like protein ESPL1; ESP1; extra spindle pole bodies 1, separase; extra spindle pole bodies homolog 1; extra spindle poles like 1; extra spindle poles-like 1 protein; SEPA; Separase; separin; separin, cysteine protease.

• Gene ID:

  9700

• Swiss Prot:

  Q14674

• Accession Number:

  NP_036423.4

• Reactivity:

  Human|Mouse

• Immunogen:

  The antiserum was produced against synthesized peptide derived from human SEPARASE.

• Target:

  Caspase-like protease, which plays a central role in the chromosome segregation by cleaving the SCC1/RAD21 subunit of the cohesin complex at the onset of anaphase. During most of the cell cycle, it is inactivated by different mechanisms.

• Clonality:

  Polyclonal

• Type:

  Polyclonal Antibody

• Applications:

  Enzyme-linked immunosorbent assay|Immunocytochemistry|Immunofluorescence|Immunohistochemistry|Immunohistochemistry-Paraffin|Western blot

• Purification:

  The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

• Assay Protocol:

  Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

• Dilution:

  The optimal working dilution should be determined by the end user.

• Format:

  Liquid

• Reconstitution:

  -20°C

• Molecular Weight:

  233 kDa

• Notes:

  Formerly GWB-ASC106

• Specificity:

  SEPARASE (Ab-801) antibody detects endogenous levels of total SEPARASE protein.

• NCBI Gene Symbol:

  ESPL1

• Host or Source:

  Rabbit

• Protein Name:

  Separin

• Gene Name URL:

  ESPL1

• CAS Number:

  9007-83-4