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CXCR2 Antibody (Phospho-Ser347)

CAT: 0247-OAAF00235-100UGSize: 100 µgDry Ice: NoHazardous: No
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CAT#:0247-OAAF00235-100UGSize:100 µg
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Description
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CAS Number
9007-83-4
Gene Name
C-X-C motif chemokine receptor 2
Gene Aliases
CD182; CDw128b; chemokine (CXC) receptor 2; CMKAR2; C-X-C chemokine receptor type 2; CXCR-2; CXC-R2; CXCR2 gene for IL8 receptor type B; GRO/MGSA receptor; high affinity interleukin-8 receptor B; IL-8 receptor type 2; IL-8R B; IL8R2; IL8RA; IL8RB; interleukin 8 receptor type 2; interleukin 8 receptor, beta; interleukin-8 receptor type B; WHIMS2.
Gene ID
3579
Swiss Prot
P25025
Accession Number
NP_001161770.1
Reactivity
Human|Mouse
Immunogen
The antiserum was produced against synthesized peptide derived from human IL-8R beta/CDw128 beta around the phosphorylation site of Ser347.
Target
Receptor for interleukin-8 which is a powerful neutrophil chemotactic factor. Binding of IL-8 to the receptor causes activation of neutrophils. This response is mediated via a G-protein that activates a phosphatidylinositol-calcium second messenger system. Binds to IL-8 with high affinity. Also binds with high affinity to CXCL3, GRO/MGSA and NAP-2.
Clonality
Polyclonal
Type
Polyclonal Antibody
Applications
Enzyme-linked immunosorbent assay|Immunocytochemistry|Immunofluorescence|Immunohistochemistry|Immunohistochemistry-Paraffin|Western blot
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific phosphopeptide. The antibody against non-phosphopeptide was removed by chromatography using non-phosphopeptide corresponding to the phosphorylation.
Assay Protocol
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol
Dilution
The optimal working dilution should be determined by the end user.
Format
Liquid
Reconstitution
-20°C
Molecular Weight
40 kDa
Notes
Formerly GWB-ASB500
Specificity
IL-8R beta/CDw128 beta (Phospho-Ser347) Antibody detects endogenous levels of IL-8R beta/CDw128 beta only when phosphorylated at serine347.
NCBI Gene Symbol
CXCR2
Host or Source
Rabbit
Protein Name
C-X-C chemokine receptor type 2
Gene Name URL
CXCR2

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