KRT18 Antibody (Phospho-Ser52)

• Gene Name:

  Keratin 18

• Gene Aliases:

  Cell proliferation-inducing gene 46 protein; CK-18; CYK18; cytokeratin 18; Cytokeratin-18; K18; keratin 18, type I; keratin, type I cytoskeletal 18; Keratin-18.

• Gene ID:

  3875

• Swiss Prot:

  P05783

• Accession Number:

  NP_000215.1

• Reactivity:

  Human|Mouse|Rat

• Immunogen:

  The antiserum was produced against synthesized peptide derived from human Keratin 18 around the phosphorylation site of Ser52.

• Target:

  Involved in the uptake of thrombin-antithrombin complexes by hepatic cells (By similarity) . When phosphorylated, plays a role in filament reorganization. Involved in the delivery of mutated CFTR to the plasma membrane. Together with KRT8, is involved in interleukin-6 (IL-6) -mediated barrier protection.

• Clonality:

  Polyclonal

• Type:

  Polyclonal Antibody

• Applications:

  Enzyme-linked immunosorbent assay|Immunocytochemistry|Immunofluorescence|Immunohistochemistry|Immunohistochemistry-Paraffin|Western blot

• Purification:

  The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

• Assay Protocol:

  Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

• Dilution:

  The optimal working dilution should be determined by the end user.

• Format:

  Liquid

• Reconstitution:

  -20°C

• Molecular Weight:

  48 kDa

• Notes:

  Formerly GWB-ASB398

• Specificity:

  Cytokeratin 18 (Phospho-Ser52) antibody detects endogenous levels of Cytokeratin 18 only when phosphorylated at serine 52.

• NCBI Gene Symbol:

  KRT18

• Host or Source:

  Rabbit

• Protein Name:

  Keratin, type I cytoskeletal 18

• Gene Name URL:

  KRT18

• CAS Number:

  9007-83-4