Products for Research Use Only
RegisterLogin

CENPA Antibody (Phospho-Ser7)

CAT: 0247-OAAF00181-100UGSize: 100 µgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0247-OAAF00181-100UGSize:100 µg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
CAS Number
9007-83-4
Gene Name
Centromere protein A
Gene Aliases
CenH3; CENP-A; centromere autoantigen A; Centromere protein A; centromere protein A, 17kDa; centromere-specific histone; histone H3-like centromeric protein A.
Gene ID
1058
Swiss Prot
P49450
Accession Number
NP_001035891.1
Reactivity
Human|Mouse|Rat
Immunogen
The antiserum was produced against synthesized peptide derived from human Centromeric Protein A around the phosphorylation site of Ser7.
Target
Histone H3-like nucleosomal protein that is specifically found in centromeric nucleosomes (PubMed:7962047, PubMed:9024683, PubMed:11756469, PubMed:14667408, PubMed:15702419, PubMed:15475964, PubMed:15282608, PubMed:17651496, PubMed:19114591, PubMed:27499292, PubMed:20739937) . Replaces conventional H3 in the nucleosome core of centromeric chromatin at the inner plate of the kinetochore (PubMed:18072184) . The presence of CENPA subtly modifies the nucleosome structure and the way DNA is wrapped around the nucleosome and gives rise to protruding DNA ends that are less well-ordered and rigid compared to nucleosomes containing histone H3 (PubMed:27499292, PubMed:26878239) . May serve as an epigenetic mark that propagates centromere identity through replication and cell division (PubMed:15475964, PubMed:15282608, PubMed:26878239, PubMed:20739937, PubMed:21478274) . Required for recruitment and assembly of kinetochore proteins, and as a consequence required for progress through mitosis, chromosome segregation and cytokinesis (PubMed:11756469, PubMed:14667408, PubMed:18072184, PubMed:23818633, PubMed:25556658, PubMed:27499292) .
Clonality
Polyclonal
Type
Polyclonal Antibody
Applications
Enzyme-linked immunosorbent assay|Immunocytochemistry|Immunofluorescence
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Assay Protocol
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol
Dilution
The optimal working dilution should be determined by the end user.
Format
Liquid
Reconstitution
-20°C
Molecular Weight
15 kDa
Notes
Formerly GWB-ASB385
Specificity
Centromeric Protein A (Phospho-Ser7) antibody detects endogenous levels of Centromeric Protein A only when phosphorylated at serine 7.
NCBI Gene Symbol
CENPA
Host or Source
Rabbit
Protein Name
Histone H3-like centromeric protein A
Gene Name URL
CENPA

Related Products

CatalogName
OACA09352-50UGCENPA Antibody
OACA09352-100UGCENPA Antibody
OAAF00998-100UGCENPA Antibody
OAAF02892-100UGCENPA Antibody
OPPA01301-5UGCENPA Protein
ARP46041_P050-25ULCENPA Antibody - middle region
OCOA00615-20UGCENPA Protein Lysate
AAP46040-100UGCENPA Peptide (AAP46040)
OCOA15145-20UGCENPA Protein Lysate
AAP46041-100UGCENPA Peptide (AAP46041)

Alternative Products

CatalogName
AF2330-01Phospho-CENPA (Ser7) Antibody
bs-3066RPhospho-CENPA (Ser7) Polyclonal Antibody
70R-33499CENPA antibody (Ser7)
GTR17724455-01Phospho-CENPA (Ser7) Rabbit Polyclonal Antibody
SL3066R-01Rabbit Anti-Phospho-CENPA (Ser7) antibody
bs-3066R-Cy7Phospho-CENPA (Ser7) Polyclonal Antibody, Cy7 Conjugated
bs-3066R-APCPhospho-CENPA (Ser7) Polyclonal Antibody, APC Conjugated
C04459Cy3CENPA (Phospho-Ser7) Polyclonal Antibody Cy3 Conjugated
bs-3066R-PEPhospho-CENPA (Ser7) Polyclonal Antibody, PE Conjugated
bs-3066R-Cy3Phospho-CENPA (Ser7) Polyclonal Antibody, Cy3 Conjugated

Popular Products