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STAT5B Antibody (Phospho-Ser731)

CAT: 0247-OAAF00061-100UGSize: 100 µgDry Ice: NoHazardous: No
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CAT#:0247-OAAF00061-100UGSize:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
9007-83-4
Gene Name
Signal transducer and activator of transcription 5A|signal transducer and activator of transcription 5B
Gene Aliases
Epididymis secretory sperm binding protein; GHISID2; MGF; signal transducer and activator of transcription 5A; signal transducer and activator of transcription 5B; STAT5; transcription factor STAT5B.
Gene ID
6776|6777
Swiss Prot
P42229|P51692
Accession Number
NP_036580.2
Reactivity
Human|Mouse|Rat
Immunogen
The antiserum was produced against synthesized peptide derived from human STAT5B around the phosphorylation site of Ser731.
Target
Carries out a dual function: signal transduction and activation of transcription (PubMed:29844444) . Mediates cellular responses to the cytokine KITLG/SCF and other growth factors. Binds to the GAS element and activates PRL-induced transcription. Positively regulates hematopoietic/erythroid differentiation.|Carries out a dual function: signal transduction and activation of transcription. Mediates cellular responses to the cytokine KITLG/SCF and other growth factors. Mediates cellular responses to ERBB4. May mediate cellular responses to activated FGFR1, FGFR2, FGFR3 and FGFR4. Binds to the GAS element and activates PRL-induced transcription. Regulates the expression of milk proteins during lactation.
Clonality
Polyclonal
Type
Polyclonal Antibody
Applications
Enzyme-linked immunosorbent assay|Immunofluorescence|Immunohistochemistry|Immunohistochemistry-Paraffin|Western blot
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Assay Protocol
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol
Dilution
The optimal working dilution should be determined by the end user.
Format
Liquid
Reconstitution
-20°C
Molecular Weight
89 kDa
Notes
Formerly GWB-ASB077
Specificity
STAT5B (phospho-Ser731) antibody detects endogenous levels of STAT5B only when phosphorylated at serine 731
NCBI Gene Symbol
STAT5A|STAT5B
Host or Source
Rabbit
Protein Name
Signal transducer and activator of transcription 5A|Signal transducer and activator of transcription 5B
Gene Name URL
STAT5A|STAT5B