STAT5B Antibody (Phospho-Ser731)

• Gene Name:

  Signal transducer and activator of transcription 5A|signal transducer and activator of transcription 5B

• Gene Aliases:

  Epididymis secretory sperm binding protein; GHISID2; MGF; signal transducer and activator of transcription 5A; signal transducer and activator of transcription 5B; STAT5; transcription factor STAT5B.

• Gene ID:

  6776|6777

• Swiss Prot:

  P42229|P51692

• Accession Number:

  NP_036580.2

• Reactivity:

  Human|Mouse|Rat

• Immunogen:

  The antiserum was produced against synthesized peptide derived from human STAT5B around the phosphorylation site of Ser731.

• Target:

  Carries out a dual function: signal transduction and activation of transcription (PubMed:29844444) . Mediates cellular responses to the cytokine KITLG/SCF and other growth factors. Binds to the GAS element and activates PRL-induced transcription. Positively regulates hematopoietic/erythroid differentiation.|Carries out a dual function: signal transduction and activation of transcription. Mediates cellular responses to the cytokine KITLG/SCF and other growth factors. Mediates cellular responses to ERBB4. May mediate cellular responses to activated FGFR1, FGFR2, FGFR3 and FGFR4. Binds to the GAS element and activates PRL-induced transcription. Regulates the expression of milk proteins during lactation.

• Clonality:

  Polyclonal

• Type:

  Polyclonal Antibody

• Applications:

  Enzyme-linked immunosorbent assay|Immunofluorescence|Immunohistochemistry|Immunohistochemistry-Paraffin|Western blot

• Purification:

  The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

• Assay Protocol:

  Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

• Dilution:

  The optimal working dilution should be determined by the end user.

• Format:

  Liquid

• Reconstitution:

  -20°C

• Molecular Weight:

  89 kDa

• Notes:

  Formerly GWB-ASB077

• Specificity:

  STAT5B (phospho-Ser731) antibody detects endogenous levels of STAT5B only when phosphorylated at serine 731

• NCBI Gene Symbol:

  STAT5A|STAT5B

• Host or Source:

  Rabbit

• Protein Name:

  Signal transducer and activator of transcription 5A|Signal transducer and activator of transcription 5B

• Gene Name URL:

  STAT5A|STAT5B

• CAS Number:

  9007-83-4