TIMP2 Antibody

• Gene Name:

  TIMP metallopeptidase inhibitor 2

• Gene Aliases:

  DDC8, CSC-21K

• Gene ID:

  7077

• Swiss Prot:

  P16035

• Accession Number:

  NP_003246.1

• Reactivity:

  Human, Mouse

• Immunogen:

  This TIMP2 antibody is generated from a mouse immunized with arecombinant protein of human TIMP2.

• Target:

  This gene is a member of the TIMP gene family. The proteins encoded by this gene family are natural inhibitors of the matrix metalloproteinases, a group of peptidases involved in degradation of the extracellular matrix. In addition to an inhibitory role against metalloproteinases, the encoded protein has a unique role among TIMP family members in its ability to directly suppress the proliferation of endothelial cells. As a result, the encoded protein may be critical to the maintenance of tissue homeostasis by suppressing the proliferation of quiescent tissues in response to angiogenic factors, and by inhibiting protease activity in tissues undergoing remodelling of the extracellular matrix.

• Clonality:

  Monoclonal

• Clone:

  1554CT494.262.47

• Type:

  Monoclonal Antibody

• Applications:

  WB

• Purification:

  Protein G column purification, followed by dialysis against PBS

• Assay Protocol:

  Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

• Concentration:

  500 ug/mL

• Homology:

  Human, Mouse

• Format:

  Liquid

• Reconstitution:

  Maintain refrigerated at 2-8C for up to 2 weeks. For long term storage store at -20C in small aliquots to prevent freeze-thaw cycles.

• Molecular Weight:

  24 kDa

• Fragment:

  IgG1, kappa

• NCBI Gene Symbol:

  TIMP2

• Host or Source:

  Mouse

• Gene Name URL:

  TIMP2

• CAS Number:

  9007-83-4

• Nucleotide Accession Number:

  NM_003255.4