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PLCG1 Antibody - middle region

CAT: 0247-OAAB21615-400ULSize: 400 µLDry Ice: NoHazardous: No
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CAT#:0247-OAAB21615-400ULSize:400 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
9007-83-4
Gene Name
Phospholipase C gamma 1
Gene Aliases
PLC1, NCKAP3, PLC-II, PLC148, PLCgamma1
Gene ID
5335
Swiss Prot
P19174
Accession Number
NP_002651.2
Reactivity
Human, Mouse
Immunogen
This PLCG1 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 758-790 amino acids from the Central region of human PLCG1.
Target
The protein encoded by this gene catalyzes the formation of inositol 1,4,5-trisphosphate and diacylglycerol from phosphatidylinositol 4,5-bisphosphate. This reaction uses calcium as a cofactor and plays an important role in the intracellular transduction of receptor-mediated tyrosine kinase activators. For example, when activated by SRC, the encoded protein causes the Ras guanine nucleotide exchange factor RasGRP1 to translocate to the Golgi, where it activates Ras. Also, this protein has been shown to be a major substrate for heparin-binding growth factor 1 (acidic fibroblast growth factor) -activated tyrosine kinase. Two transcript variants encoding different isoforms have been found for this gene.
Clonality
Polyclonal
Clone
RB53784
Type
Polyclonal Antibody
Applications
WB
Purification
Protein A column purification, followed by peptide affinity purification
Assay Protocol
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol
Concentration
500 ug/mL
Homology
Human, Mouse
Format
Liquid
Reconstitution
Maintain refrigerated at 2-8C for up to 2 weeks. For long term storage store at -20C in small aliquots to prevent freeze-thaw cycles.
Molecular Weight
149 kDa
Fragment
Rabbit Ig
NCBI Gene Symbol
PLCG1
Host or Source
Rabbit
Gene Name URL
PLCG1
Nucleotide Accession Number
NM_002660.2

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