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CDK5 Antibody

CAT: 0247-OAAB21019-200ULSize: 200 µLDry Ice: NoHazardous: No
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CAT#:0247-OAAB21019-200ULSize:200 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
9007-83-4
Gene Name
Cyclin-dependent kinase 5
Gene Aliases
LIS7, PSSALRE
Gene ID
1020
Swiss Prot
Q00535
Accession Number
NP_001157882.1
Reactivity
Human, Mouse
Immunogen
This CDK5 antibody is generated from a mouse immunized with a recombinant protein of human CDK5.
Target
This gene encodes a proline-directed serine/threonine kinase that is a member of the cyclin-dependent kinase family of proteins. Unlike other members of the family, the protein encoded by this gene does not directly control cell cycle regulation. Instead the protein, which is predominantly expressed at high levels in mammalian postmitotic central nervous system neurons, functions in diverse processes such as synaptic plasticity and neuronal migration through phosphorylation of proteins required for cytoskeletal organization, endocytosis and exocytosis, and apoptosis. In humans, an allelic variant of the gene that results in undetectable levels of the protein has been associated with lethal autosomal recessive lissencephaly-7. Alternative splicing results in multiple transcript variants.
Clonality
Monoclonal
Clone
1552CT262.105.8
Type
Monoclonal Antibody
Applications
WB, IF, IHC-P, FC, ELISA
Purification
Protein G column purification, followed by dialysis against PBS
Assay Protocol
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol
Concentration
0.5 mg/ml
Format
Liquid// PBS with 0.09% (W/V) sodium azide
Reconstitution
Maintain refrigerated at 2-8° C for up to 2 weeks. For long term storage store at -20° C in small aliquots to prevent freeze-thaw cycles.
Molecular Weight
33 kDa
Fragment
IgG1, kappa
NCBI Gene Symbol
CDK5
Host or Source
Mouse
Gene Name URL
CDK5
Nucleotide Accession Number
NM_001164410.2

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