CDK5 Antibody

• Gene Name:

  Cyclin-dependent kinase 5

• Gene Aliases:

  LIS7, PSSALRE

• Gene ID:

  1020

• Swiss Prot:

  Q00535

• Accession Number:

  NP_001157882.1

• Reactivity:

  Human, Mouse

• Immunogen:

  This CDK5 antibody is generated from a mouse immunized with a recombinant protein of human CDK5.

• Target:

  This gene encodes a proline-directed serine/threonine kinase that is a member of the cyclin-dependent kinase family of proteins. Unlike other members of the family, the protein encoded by this gene does not directly control cell cycle regulation. Instead the protein, which is predominantly expressed at high levels in mammalian postmitotic central nervous system neurons, functions in diverse processes such as synaptic plasticity and neuronal migration through phosphorylation of proteins required for cytoskeletal organization, endocytosis and exocytosis, and apoptosis. In humans, an allelic variant of the gene that results in undetectable levels of the protein has been associated with lethal autosomal recessive lissencephaly-7. Alternative splicing results in multiple transcript variants.

• Clonality:

  Monoclonal

• Clone:

  1552CT262.105.8

• Type:

  Monoclonal Antibody

• Applications:

  WB, IF, IHC-P, FC, ELISA

• Purification:

  Protein G column purification, followed by dialysis against PBS

• Assay Protocol:

  Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

• Concentration:

  0.5 mg/ml

• Format:

  Liquid// PBS with 0.09% (W/V) sodium azide

• Reconstitution:

  Maintain refrigerated at 2-8° C for up to 2 weeks. For long term storage store at -20° C in small aliquots to prevent freeze-thaw cycles.

• Molecular Weight:

  33 kDa

• Fragment:

  IgG1, kappa

• NCBI Gene Symbol:

  CDK5

• Host or Source:

  Mouse

• Gene Name URL:

  CDK5

• CAS Number:

  9007-83-4

• Nucleotide Accession Number:

  NM_001164410.2