STAT3 Antibody

• Gene Aliases :

  APRF, HIES, ADMIO, ADMIO1

• Gene ID :

  6774

• Swiss Prot :

  P40763P52631Q19S50P42227

• Reactivity :

  Mouse, Rat, Pig

• Immunogen :

  This STAT3 antibody is generated from a mouse immunized with a recombinant protein from human.

• Target :

  Signal transducer and transcription activator that mediates cellular responses to interleukins, KITLG/SCF and other growth factors. May mediate cellular responses to activated FGFR1, FGFR2, FGFR3 and FGFR4. Binds to the interleukin-6 (IL-6) - responsive elements identified in the promoters of various acute- phase protein genes. Activated by IL31 through IL31RA. Cytoplasmic STAT3 represses macroautophagy by inhibiting EIF2AK2/PKR activity. Plays an important role in host defense in methicillin-resistant S.aureus lung infection by regulating the expression of the antimicrobial lectin REG3G (By similarity) .

• Clonality :

  Monoclonal

• Type :

  Monoclonal Antibody

• Applications :

  WB

• Purification :

  This antibody is purified through a protein G column, followed by dialysis against PBS.

• Assay Protocol :

  Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

• Homology :

  Mouse; Pig; Rat

• Format :

  Liquid. Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.

• Reconstitution :

  Maintain refrigerated at 2-8C for up to 2 weeks. For long term storage store at -20C in small aliquots to prevent freeze-thaw cycles.

• Molecular Weight :

  88 kDa

• Fragment :

  IgG2a, kappa

• NCBI Gene Symbol :

  STAT3

• Host or Source :

  Mouse

• Gene Name URL :

  STAT3

• CAS Number :

  9007-83-4