Products for Research Use Only
RegisterLogin

ATG7 Antibody

CAT: 0247-OAAB13622-400ULSize: 400 µLDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0247-OAAB13622-400ULSize:400 µL
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
CAS Number
9007-83-4
Gene Aliases
GSA7, APG7L, APG7-LIKE
Gene ID
10533
Swiss Prot
O95352
Accession Number
NP_001129503.2
Reactivity
Human, Mouse
Immunogen
This ATG7 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 494-523 amino acids from human ATG7.
Target
Macroautophagy is the major inducible pathway for the general turnover of cytoplasmic constituents in eukaryotic cells, it is also responsible for the degradation of active cytoplasmic enzymes and organelles during nutrient starvation. Macroautophagy involves the formation of double-membrane bound autophagosomes which enclose the cytoplasmic constituent targeted for degradation in a membrane bound structure, which then fuse with the lysosome (or vacuole) releasing a single-membrane bound autophagic bodies which are then degraded within the lysosome (or vacuole) . APG7 functions as an E1 enzyme essential for multisubstrates such as GABARAPL1 and ATG12. APG3L is an E2-like conjugating enzyme facilitating covalent binding of APG8 (MAP1LC3) to phosphatidylethanolamine (PE) . APG7 (an E1-like enzyme) facilitates this reaction by forming an E1-E2 complex with APG3. Formation of the PE conjugate is essential for autophagy.
Clonality
Polyclonal
Type
Polyclonal Antibody
Applications
IHC-P, WB
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Assay Protocol
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol
Concentration
Approximately 0.5mg/ml. Actual concentration varies with each lot.
Homology
Rat
Format
Liquid// PBS with 0.09% (W/V) sodium azide.
Reconstitution
Maintain refrigerated at 2-8C for up to 2 weeks. For long term storage store at -20C in small aliquots to prevent freeze-thaw cycles.
Molecular Weight
78 kDa
Fragment
Ig
NCBI Gene Symbol
ATG7
Host or Source
Rabbit
Protein Name
Ubiquitin-like modifier-activating enzyme ATG7
Gene Name URL
ATG7

Related Products

CatalogName
OCOA01757-20UGATG7 Protein Lysate
OCOA19305-20UGATG7 Protein Lysate
OPCD01532-50UGATG7 Recombinant Protein
OPCD01532-200UGATG7 Recombinant Protein
OPCD01532-10UGATG7 Recombinant Protein
OKCD02038-96WATG7 ELISA Kit (Human)
OKCD09287-96WATG7 ELISA Kit (Mouse)
OKCD09287ATG7 ELISA Kit (Mouse) (OKCD09287)
OKAN06278ATG7 ELISA Kit (Human) (OKAN06278)
OKAN06492ATG7 ELISA Kit (Mouse) (OKAN06492)

Alternative Products

CatalogName
MBS2523744-01ATG7 Antibody

Popular Products