ACTA1 Antibody

• Gene Aliases:

  ACTA, ASMA, CFTD, MPFD, NEM1, NEM2, NEM3, SHPM, CFTD1, CFTDM

• Gene ID:

  58

• Swiss Prot:

  P68133

• Accession Number:

  NP_001091.1

• Reactivity:

  Human

• Immunogen:

  This ACTA1 monoclonal antibody is generated from mouse immunized with ACTA1 recombinant protein.

• Target:

  The product encoded by this gene belongs to the actin family of proteins, which are highly conserved proteins that play a role in cell motility, structure and integrity. Alpha, beta and gamma actin isoforms have been identified, with alpha actins being a major constituent of the contractile apparatus, while beta and gamma actins are involved in the regulation of cell motility. This actin is an alpha actin that is found in skeletal muscle. Mutations in this gene cause nemaline myopathy type 3, congenital myopathy with excess of thin myofilaments, congenital myopathy with cores, and congenital myopathy with fiber-type disproportion, diseases that lead to muscle fiber defects.

• Clonality:

  Monoclonal

• Clone:

  337CT30.10.1

• Type:

  Monoclonal Antibody

• Applications:

  WB, IHC-P, FC

• Purification:

  This antibody is purified through a protein G column, followed by dialysis against PBS.

• Assay Protocol:

  Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

• Concentration:

  Approximately 0.5mg/ml. Actual concentration varies with each lot.

• Homology:

  Bovine, Chicken, Mouse, Pig, Rabbit, Rat

• Format:

  Liquid.// PBS with 0.09% (W/V) sodium azide.

• Reconstitution:

  Maintain refrigerated at 2-8C for up to 2 weeks. For long term storage store at -20C in small aliquots to prevent freeze-thaw cycles.

• Molecular Weight:

  42 kDa

• Fragment:

  IgG1, k

• NCBI Gene Symbol:

  ACTA1

• Host or Source:

  Mouse

• Protein Name:

  Actin, alpha skeletal muscle

• Gene Name URL:

  ACTA1

• CAS Number:

  9007-83-4