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YWHAQ

CAT: 0247-AVARP02062_P050Size: 100 µLDry Ice: NoHazardous: No
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CAT#:0247-AVARP02062_P050Size:100 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Gene Name
Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide
Gene Aliases
1C5, HS1, 14-3-3
Gene ID
10971
Swiss Prot
P27348
Accession Number
NP_006817
Reactivity
Human, Mouse, Rat, Cow, Dog, Guinea Pig, Zebrafish
Immunogen
The immunogen is a synthetic peptide directed towards the N terminal region of human YWHAQ
Target
YWHAQ belongs to the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals, and this protein is 99% identical to the mouse and rat orthologs. This gene is upregulated in patients with amyotrophic lateral sclerosis.This gene product belongs to the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals, and this protein is 99% identical to the mouse and rat orthologs. This gene is upregulated in patients with amyotrophic lateral sclerosis. It contains in its 5' UTR a 6 bp tandem repeat sequence which is polymorphic, however, there is no correlation between the repeat number and the disease.
Partner Proteins
UBC; TNFAIP3; TRIM42; RAF1; PIK3R2; PIK3C3; FUS; DTL; MAPT; ABL1; SGK1; SIK3; SUMO2; TUBGCP3; IRS4; HDAC5; HDAC4; STAU1; MDM2; TGM2; SMS; ALDH7A1; YWHAZ; YWHAH; GNAI3; G6PD; EIF5; EEF2; ECHS1; CAPNS1; CAPN1; LDHB; YWHAG; YWHAB; VCL; UBE2V1; TXNDC5; SMEK2
Clonality
Polyclonal
Type
Polyclonal Antibody
Sequence
SVAYKNVVGGRRSAWRVISSIEQKTDTSDKKLQLIKDYREKVESELRSIC
Applications
IHC, WB
Purification
Affinity Purified
Assay Protocol
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol
Concentration
0.5 mg/ml
Homology
Cow: 100%; Dog: 100%; Guinea Pig: 100%; Human: 100%; Mouse: 100%; Rat: 100%; Zebrafish: 75%
Format
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reconstitution
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
Molecular Weight
28kDa
Protein Length
245
NCBI Gene Symbol
YWHAQ
Host or Source
Rabbit
Protein Name
14-3-3 protein theta
Gene Name URL
YWHAQ
Nucleotide Accession Number
NM_006826

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