Products for Research Use Only
RegisterLogin

TNFSF10

CAT: 0247-AVARP02040_P050Size: 100 µLDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0247-AVARP02040_P050Size:100 µL
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Gene Name
Tumor necrosis factor (ligand) superfamily, member 10
Gene Aliases
TL2, APO2L, CD253, TRAIL, Apo-2L, TNLG6A
Gene ID
8743
Swiss Prot
P50591
Accession Number
NP_003801
Reactivity
Human, Dog, Pig
Immunogen
The immunogen is a synthetic peptide directed towards the N terminal region of human TNFSF10
Target
TNFSF10 is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This protein preferentially induces apoptosis in transformed and tumor cells, but does not appear to kill normal cells although it is expressed at a significant level in most normal tissues. This protein binds to several members of TNF receptor superfamily including TNFRSF10A/TRAILR1, TNFRSF10B/TRAILR2, TNFRSF10C/TRAILR3, TNFRSF10D/TRAILR4, and possibly also to TNFRSF11B/OPG. The activity of this protein may be modulated by binding to the decoy receptors TNFRSF10C/TRAILR3, TNFRSF10D/TRAILR4, and TNFRSF11B/OPG that cannot induce apoptosis. The binding of this protein to its receptors has been shown to trigger the activation of MAPK8/JNK, caspase 8, and caspase 3.
Partner Proteins
CASP8; CASP3; CFLAR; TNFRSF10B; FADD; RIPK1; TRAF2; TNFAIP3; SOCS3; RBM48; TNFRSF10D; TNFRSF10C; TNFRSF10A; TNFSF10; TNFRSF11B; ACP5; IER3; CREBBP; SP3; SP1; HDAC5; HDAC4; HDAC3; HDAC2; HDAC1; HIST3H3
Clonality
Polyclonal
Type
Polyclonal Antibody
Sequence
CFLKEDDSYWDPNDEESMNSPCWQVKWQLRQLVRKMILRTSEETISTVQE
Applications
WB
Purification
Affinity Purified
Assay Protocol
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol
Concentration
0.5 mg/ml
Homology
Dog: 80%; Human: 100%; Pig: 78%
Format
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reconstitution
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
Molecular Weight
33kDa
Protein Length
281
NCBI Gene Symbol
TNFSF10
Host or Source
Rabbit
Protein Name
Tumor necrosis factor ligand superfamily member 10
Gene Name URL
TNFSF10
Nucleotide Accession Number
NM_003810

Related Products

CatalogName
OAAN01427-100ULTNFSF12 Antibody
OACA10043-50UGTNFSF11 Antibody
OAAJ06843-100ULTNFSF13 Antibody
OAAJ07480-100ULTNFSF11 Antibody
OAAJ01992-100ULTNFSF13 Antibody
OACD00261-100ULTNFSF11 Antibody
OAAJ07910-100ULTNFSF12 Antibody
OACD00262-1MLTNFSF11 Antibody
OACA03855-100UGTNFSF11 Antibody
OACD06904-1MLTNFSF11 Antibody

Alternative Products

CatalogName
MBS8561234-01TNFSF10
GTR18157133-01TNFSF10 Antibody

Popular Products