Anti-MCRS1

• Gene Name :

  Microspherule protein 1

• Gene Aliases :

  P78, MCRS2, MSP58, INO80Q, ICP22BP

• Gene ID :

  10445

• Swiss Prot :

  Q96EZ8

• Accession Number :

  NP_001012300.1

• Reactivity :

  Human

• Immunogen :

  The immunogen is a synthetic peptide directed towards the N terminal region of human MCRS1

• Target :

  Modulates the transcription repressor activity of DAXX by recruiting it to the nucleolus. As part of the NSL complex it may be involved in acetylation of nucleosomal histone H4 on several lysine residues. Putative regulatory component of the chromatin remodeling INO80 complex which is involved in transcriptional regulation, DNA replication and probably DNA repair. May also be an inhibitor of TERT telomerase activity. Binds to G-quadruplex structures in mRNA (PubMed:16571602) . Binds to RNA homopolymer poly (G) and poly (U) .

• Clonality :

  Polyclonal

• Type :

  Polyclonal Antibody

• Sequence :

  GTASRSEDEESLAGQKRASSQALGTIPKRRSSSRFIKRKKFDDELVESSL

• Applications :

  WB

• Purification :

  Affinity purified

• Assay Protocol :

  Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

• Concentration :

  0.5 mg/ml

• Format :

  Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

• Reconstitution :

  For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.

• Molecular Weight :

  50 kDa

• Protein Length :

  462

• NCBI Gene Symbol :

  MCRS1

• Host or Source :

  Rabbit

• Protein Name :

  Microspherule protein 1

• Gene Name URL :

  MCRS1

• CAS Number :

  9007-83-4

• Nucleotide Accession Number :

  NM_001012300.1