Anti-DDI2

• Gene Name :

  DNA damage inducible 1 homolog 2

• Gene ID :

  84301

• Swiss Prot :

  Q5TDH0-2

• Accession Number :

  NP_115717.3

• Reactivity :

  Human

• Immunogen :

  The immunogen is a synthetic peptide directed towards the middle region of human DDI2

• Target :

  Aspartic protease that mediates the cleavage of NFE2L1/NRF1 at 'Leu-104', thereby promoting release of NFE2L1/NRF1 from the endoplasmic reticulum membrane. Ubiquitination of NFE2L1/NRF1 is a prerequisite for cleavage, suggesting that DDI2 specifically recognizes and binds ubiquitinated NFE2L1/NRF1.

• Clonality :

  Polyclonal

• Type :

  Polyclonal Antibody

• Sequence :

  VPGTSSPRQRQPPGTQQSHSSPGEITSSPQGLDNPALLRDMLLANPHELS

• Applications :

  WB

• Purification :

  Affinity purified

• Assay Protocol :

  Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

• Concentration :

  0.5 mg/ml

• Format :

  Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

• Reconstitution :

  For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.

• Molecular Weight :

  23 kDa

• Protein Length :

  211

• NCBI Gene Symbol :

  DDI2

• Host or Source :

  Rabbit

• Protein Name :

  Protein DDI1 homolog 2

• Gene Name URL :

  DDI2

• CAS Number :

  9007-83-4

• Nucleotide Accession Number :

  NM_032341.4