DMC1 Antibody - middle region

• Gene Name:

  DNA meiotic recombinase 1

• Gene Aliases:

  DMC1H, LIM15, dJ199H16.1

• Gene ID:

  11144

• Swiss Prot:

  Q14565

• Accession Number:

  NP_008999.2

• Reactivity:

  Human

• Immunogen:

  The immunogen is a synthetic peptide directed towards the middle region of human DMC1

• Target:

  This gene encodes a member of the superfamily of recombinases (also called DNA strand-exchange proteins) . Recombinases are important for repairing double-strand DNA breaks during mitosis and meiosis. This protein, which is evolutionarily conserved, is reported to be essential for meiotic homologous recombination and may thus play an important role in generating diversity of genetic information. Alternative splicing results in multiple transcript variants.

• Partner Proteins:

  KCTD17; NIF3L1; GORASP2; DMC1; SDCBP; PSMA3; TRIM23; RAD51; BRCA2; RAD54B; RPA1; DNAJA3

• Clonality:

  Polyclonal

• Type:

  Polyclonal Antibody

• Sequence:

  YPGGKIIFIDTENTFRPDRLRDIADRFNVDHDAVLDNVLYARAYTSEHQM

• Applications:

  WB

• Purification:

  Affinity purified

• Assay Protocol:

  Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

• Concentration:

  0.5 mg/ml

• Format:

  Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

• Reconstitution:

  For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.

• Molecular Weight:

  37 kDa

• Protein Length:

  340

• NCBI Gene Symbol:

  DMC1

• Host or Source:

  Rabbit

• Protein Name:

  Meiotic recombination protein DMC1/LIM15 homolog

• Gene Name URL:

  DMC1

• CAS Number:

  9007-83-4

• Nucleotide Accession Number:

  NM_007068.3