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EIF2B3 Antibody - middle region

CAT: 0247-ARP66344_P050-25ULSize: 25 µLDry Ice: NoHazardous: No
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CAT#:0247-ARP66344_P050-25ULSize:25 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
9007-83-4
Gene Aliases
EIF-2B, EIF2Bgamma
Gene ID
8891
Swiss Prot
Q9NR50
Accession Number
NP_065098
Reactivity
Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Yeast
Immunogen
The immunogen is a synthetic peptide directed towards the middle region of Human EIF2B3
Target
The protein encoded by this gene is one of the subunits of initiation factor eIF2B, which catalyzes the exchange of eukaryotic initiation factor 2-bound GDP for GTP. It has also been found to function as a cofactor of hepatitis C virus internal ribosome entry site-mediated translation. Mutations in this gene have been associated with leukodystrophy with vanishing white matter. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Partner Proteins
UBC; C14orf166; RTCB; DIMT1; NELFB; EDC4; IGF2BP3; G3BP1; EIF2B2; EIF3C; YBX3; RFC4; QARS; NMT1; HNRNPM; MRE11A; ILF2; HNRNPU; FLII; FKBP3; DHX9; DDX1; ABCF1; FBXO6; EGFR; EIF2B5; EIF2B4; NDUFB8; EIF2B3; GOLM1; EIF2S2; EIF2S1; STC2; EIF2B1
Clonality
Polyclonal
Type
Polyclonal Antibody
Sequence
ENGSITSIRSELIPYLVRKQFSSASSQQGQEEKEEDLKKKELKSLDIYSF
Applications
WB
Purification
Affinity Purified
Assay Protocol
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol
Concentration
0.5 mg/ml
Homology
Cow: 100%; Dog: 93%; Guinea Pig: 93%; Horse: 100%; Human: 100%; Mouse: 86%; Rabbit: 93%; Rat: 93%; Yeast: 90%
Format
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reconstitution
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
Molecular Weight
50kDa
Protein Length
452
NCBI Gene Symbol
EIF2B3
Host or Source
Rabbit
Protein Name
Translation initiation factor eIF-2B subunit gamma
Gene Name URL
EIF2B3
Nucleotide Accession Number
NM_020365

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