SUCLA2 Antibody - N-terminal region

• Gene Name:

  Succinate-CoA ligase, ADP-forming, beta subunit

• Gene Aliases:

  A-SCS, A-BETA, MTDPS5, LINC00444, SCS-betaA

• Gene ID:

  8803

• Swiss Prot:

  Q9P2R7

• Accession Number:

  NP_003841

• Reactivity:

  Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Pig, Rabbit, Yeast, Zebrafish

• Target:

  Succinyl-CoA synthetase (SCS) is a mitochondrial matrix enzyme that acts as a heterodimer, being composed of an invariant alpha subunit and a substrate-specific beta subunit. The protein encoded by this gene is an ATP-specific SCS beta subunit that dimerizes with the SCS alpha subunit to form SCS-A, an essential component of the tricarboxylic acid cycle. SCS-A hydrolyzes ATP to convert succinate to succinyl-CoA. Defects in this gene are a cause of myopathic mitochondrial DNA depletion syndrome. A pseudogene of this gene has been found on chromosome 6.

• Partner Proteins:

  FAM9B; CMTM5; AGTRAP; ARL6IP1; SUMO2; UBC; gag-pol; MRPL12; RBM4; OXCT1; IDH3A; AGFG1; S100A16; NADK2; HPDL; NIT2; SEC22B; GRHPR; SUCLG1; SDHA; RRM1; AGO4; ICT1; PSMD14; ALAS2

• Clonality:

  Polyclonal

• Type:

  Polyclonal Antibody

• Sequence:

  LKGGVKIVFSPEEAKAVSSQMIGKKLFTKQTGEKGRICNQVLVCERKYPR

• Applications:

  WB

• Purification:

  Affinity Purified

• Assay Protocol:

  Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

• Concentration:

  0.5 mg/ml

• Homology:

  Cow: 100%; Dog: 100%; Guinea Pig: 93%; Horse: 100%; Human: 100%; Mouse: 86%; Pig: 100%; Rabbit: 100%; Rat: 100%; Yeast: 91%; Zebrafish: 93%

• Format:

  Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

• Reconstitution:

  For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.

• Molecular Weight:

  45kDa

• Protein Length:

  463

• NCBI Gene Symbol:

  SUCLA2

• Host or Source:

  Rabbit

• Protein Name:

  Succinyl-CoA ligase [ADP-forming] subunit beta, mitochondrial

• Gene Name URL:

  SUCLA2

• CAS Number:

  9007-83-4

• Nucleotide Accession Number:

  NM_003850