PFKFB1 Antibody - C-terminal region

• Description:

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• Gene Name:

  6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1

• Gene Aliases:

  F6PK, HL2K, PFRX

• Gene ID:

  5207

• Swiss Prot:

  Q4VBA8

• Accession Number:

  NP_002616

• Reactivity:

  Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish

• Target:

  This gene encodes a member of the family of bifunctional 6-phosphofructo-2-kinase:fructose-2,6-biphosphatase enzymes. The enzyme forms a homodimer that catalyzes both the synthesis and degradation of fructose-2,6-biphosphate using independent catalytic domains. Fructose-2,6-biphosphate is an activator of the glycolysis pathway and an inhibitor of the gluconeogenesis pathway. Consequently, regulating fructose-2,6-biphosphate levels through the activity of this enzyme is thought to regulate glucose homeostasis.

• Partner Proteins:

  PFKFB1; Prkaa2; PRKCA; PRKACA; APP; AKT1; MAPK3

• Clonality:

  Polyclonal

• Type:

  Polyclonal Antibody

• Sequence:

  CPLHTVLKLTPVAYGCKVESIYLNVEAVNTHREKPENVDITREPEEALDT

• Applications:

  WB

• Purification:

  Affinity Purified

• Assay Protocol:

  Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

• Concentration:

  0.5 mg/ml

• Homology:

  Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 93%; Rabbit: 93%; Rat: 100%; Zebrafish: 79%

• Format:

  Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

• Reconstitution:

  For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.

• Molecular Weight:

  52kDa

• Protein Length:

  471

• NCBI Gene Symbol:

  PFKFB1

• Host or Source:

  Rabbit

• Protein Name:

  6-phosphofructo-2-kinase/fructose-2, 6-biphosphatase 1 EMBL AAH96078.1

• Gene Name URL:

  PFKFB1

• CAS Number:

  9007-83-4

• Nucleotide Accession Number:

  NM_002625