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TNFAIP3 Antibody

CAT: 0247-ARP61326_P050-25ULSize: 25 µLDry Ice: NoHazardous: No
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CAT#:0247-ARP61326_P050-25ULSize:25 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
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CAS Number
9007-83-4
Gene Name
Tumor necrosis factor, alpha-induced protein 3
Gene Aliases
A20, AISBL, OTUD7C, TNFA1P2
Gene ID
7128
Swiss Prot
P21580
Accession Number
NP_006281
Reactivity
Human, Mouse, Rat, Cow, Dog, Horse, Rabbit
Immunogen
The immunogen is a synthetic peptide directed towards the following sequence LGSTMFEGYCQKCFIEAQNQRFHEAKRTEEQLRSSQRRDVPRTTQSTSRP
Target
This gene was identified as a gene whose expression is rapidly induced by the tumor necrosis factor (TNF) . The protein encoded by this gene is a zinc finger protein and ubiqitin-editing enzyme, and has been shown to inhibit NF-kappa B activation as well as TNF-mediated apoptosis. The encoded protein, which has both ubiquitin ligase and deubiquitinase activities, is involved in the cytokine-mediated immune and inflammatory responses. Several transcript variants encoding the same protein have been found for this gene.
Partner Proteins
YWHAQ; TNIP1; TNIP3; ARRDC3; RNF114; UBE2D1; UBC; TRAF2; TNFAIP3; TRIM23; ELAVL1; MALT1; OCLN; TP53; BIRC3; BIRC2; NFKB2; AXIN1; GIT2; IKBKG; LAPTM5; YWHAZ; YWHAE; RNF11; HSP90AA1; RNF5; RLIM; TRIM2; RBCK1; TRIM3; RNF14; TRIM5; TRIM8; TRAF6; SHARPIN; RNF3
Clonality
Polyclonal
Type
Polyclonal Antibody
Sequence
LGSTMFEGYCQKCFIEAQNQRFHEAKRTEEQLRSSQRRDVPRTTQSTSRP
Applications
IHC
Purification
Affinity Purified
Assay Protocol
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol
Concentration
0.5 mg/ml
Homology
Cow: 77%; Dog: 77%; Horse: 85%; Human: 100%; Mouse: 83%; Rabbit: 100%; Rat: 83%
Format
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reconstitution
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
Molecular Weight
90 kDa
Protein Length
790
NCBI Gene Symbol
TNFAIP3
Host or Source
Rabbit
Protein Name
Tumor necrosis factor alpha-induced protein 3
Gene Name URL
TNFAIP3
Nucleotide Accession Number
NM_001270507

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