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PCSK9 Antibody

CAT: 0247-ARP60837_P050Size: 100 µLDry Ice: NoHazardous: No
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CAT#:0247-ARP60837_P050Size:100 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
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CAS Number
9007-83-4
Gene Name
Proprotein convertase subtilisin/kexin type 9
Gene Aliases
FH3, PC9, FHCL3, NARC1, LDLCQ1, NARC-1, HCHOLA3
Gene ID
255738
Swiss Prot
Q8NBP7
Accession Number
NP_777596
Reactivity
Human, Pig
Immunogen
The immunogen is a synthetic peptide directed towards the following sequence RITPPRYRADEYQPPDGGSLVEVYLLDTSIQSDHREIEGRVMVTDFENVP
Target
This gene encodes a proprotein convertase belonging to the proteinase K subfamily of the secretory subtilase family. The encoded protein is synthesized as a soluble zymogen that undergoes autocatalytic intramolecular processing in the endoplasmic reticulum. The protein may function as a proprotein convertase. This protein plays a role in cholesterol homeostasis and may have a role in the differentiation of cortical neurons. Mutations in this gene have been associated with a third form of autosomal dominant familial hypercholesterolemia (HCHOLA3) .
Partner Proteins
TUBB6; UGGT1; AGK; RHOT1; DNAJC10; DNAJB11; PGRMC1; CDIPT; DNAJA2; STUB1; PDIA4; DNAJA3; SLC25A12; UBC; TRAF2; SLC25A1; RPL28; RCN1; LDLR; HSPB1; DNAJA1; SLC25A10; CLGN; BIRC2; BACE1; PCSK9
Clonality
Polyclonal
Type
Polyclonal Antibody
Sequence
RITPPRYRADEYQPPDGGSLVEVYLLDTSIQSDHREIEGRVMVTDFENVP
Applications
IHC
Purification
Affinity Purified
Assay Protocol
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol
Concentration
0.5 mg/ml
Homology
Human: 100%; Pig: 93%
Format
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reconstitution
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
Molecular Weight
74 kDa
Protein Length
692
NCBI Gene Symbol
PCSK9
Host or Source
Rabbit
Protein Name
Proprotein convertase subtilisin/kexin type 9
Gene Name URL
PCSK9
Nucleotide Accession Number
NM_174936

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