MAP3K10 Antibody - C-terminal region

• Description:

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• Gene Name:

  Mitogen-activated protein kinase kinase kinase 10

• Gene Aliases:

  MST, MLK2, MEKK10

• Gene ID:

  4294

• Swiss Prot:

  Q02779

• Accession Number:

  NP_002437

• Reactivity:

  Human, Mouse, Rat, Cow, Dog, Guinea Pig, Pig, Rabbit

• Immunogen:

  The immunogen is a synthetic peptide directed towards the C terminal region of human MAP3K10

• Target:

  The protein encoded by this gene is a member of the serine/threonine kinase family. This kinase has been shown to activate MAPK8/JNK and MKK4/SEK1, and this kinase itself can be phoshorylated, and thus activated by JNK kinases. This kinase functions preferentially on the JNK signaling pathway, and is reported to be involved in nerve growth factor (NGF) induced neuronal apoptosis.

• Partner Proteins:

  MAPK9; MAPK1; MAP3K10; MAPK14; GARS; COPS2; KIAA1804; ABL2; SH3RF1; CNKSR1; YWHAE; RACGAP1; KIF3A; DNM1L; KIF3B; DLG4; KIFAP3; MAP2K4; TUBB; PHB; HTT; CLTC; CDC42; CEACAM1; HGS; DNM1; KRTAP3-4P; KIF17; MAPK8IP2; MAPK8IP1; RAC1; HPCA; NEUROD1

• Clonality:

  Polyclonal

• Type:

  Polyclonal Antibody

• Sequence:

  TLTFAPRPRPAASRPRLDPWKLVSFGRTLTISPPSRPDTPESPGPPSVQP

• Applications:

  WB

• Purification:

  Affinity Purified

• Assay Protocol:

  Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

• Concentration:

  0.5 mg/ml

• Homology:

  Cow: 93%; Dog: 100%; Guinea Pig: 93%; Human: 100%; Mouse: 100%; Pig: 100%; Rabbit: 86%; Rat: 100%

• Format:

  Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

• Reconstitution:

  For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.

• Molecular Weight:

  104kDa

• Protein Length:

  954

• NCBI Gene Symbol:

  MAP3K10

• Host or Source:

  Rabbit

• Protein Name:

  Mitogen-activated protein kinase kinase kinase 10

• Gene Name URL:

  MAP3K10

• CAS Number:

  9007-83-4

• Nucleotide Accession Number:

  NM_002446