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MAP3K10 Antibody - C-terminal region

CAT: 0247-ARP60309_P050-25ULSize: 25 µLDry Ice: NoHazardous: No
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CAT#:0247-ARP60309_P050-25ULSize:25 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
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CAS Number
9007-83-4
Gene Name
Mitogen-activated protein kinase kinase kinase 10
Gene Aliases
MST, MLK2, MEKK10
Gene ID
4294
Swiss Prot
Q02779
Accession Number
NP_002437
Reactivity
Human, Mouse, Rat, Cow, Dog, Guinea Pig, Pig, Rabbit
Immunogen
The immunogen is a synthetic peptide directed towards the C terminal region of human MAP3K10
Target
The protein encoded by this gene is a member of the serine/threonine kinase family. This kinase has been shown to activate MAPK8/JNK and MKK4/SEK1, and this kinase itself can be phoshorylated, and thus activated by JNK kinases. This kinase functions preferentially on the JNK signaling pathway, and is reported to be involved in nerve growth factor (NGF) induced neuronal apoptosis.
Partner Proteins
MAPK9; MAPK1; MAP3K10; MAPK14; GARS; COPS2; KIAA1804; ABL2; SH3RF1; CNKSR1; YWHAE; RACGAP1; KIF3A; DNM1L; KIF3B; DLG4; KIFAP3; MAP2K4; TUBB; PHB; HTT; CLTC; CDC42; CEACAM1; HGS; DNM1; KRTAP3-4P; KIF17; MAPK8IP2; MAPK8IP1; RAC1; HPCA; NEUROD1
Clonality
Polyclonal
Type
Polyclonal Antibody
Sequence
TLTFAPRPRPAASRPRLDPWKLVSFGRTLTISPPSRPDTPESPGPPSVQP
Applications
WB
Purification
Affinity Purified
Assay Protocol
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol
Concentration
0.5 mg/ml
Homology
Cow: 93%; Dog: 100%; Guinea Pig: 93%; Human: 100%; Mouse: 100%; Pig: 100%; Rabbit: 86%; Rat: 100%
Format
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reconstitution
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
Molecular Weight
104kDa
Protein Length
954
NCBI Gene Symbol
MAP3K10
Host or Source
Rabbit
Protein Name
Mitogen-activated protein kinase kinase kinase 10
Gene Name URL
MAP3K10
Nucleotide Accession Number
NM_002446

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