ACO2 Antibody - C-terminal region

• Gene Name:

  Aconitase 2, mitochondrial

• Gene Aliases:

  ICRD, OCA8, OPA9, ACONM, HEL-S-284

• Gene ID:

  50

• Swiss Prot:

  Q99798

• Accession Number:

  NP_001089

• Reactivity:

  Human, Rat, Cow, Pig, Yeast

• Immunogen:

  The immunogen is a synthetic peptide directed towards the C terminal region of human ACO2

• Target:

  ACO2 belongs to the aconitase/IPM isomerase family. It is an enzyme that catalyzes the interconversion of citrate to isocitrate via cis-aconitate in the second step of the TCA cycle. This protein is encoded in the nucleus and functions in the mitochondrion. It was found to be one of the mitochondrial matrix proteins that are preferentially degraded by the serine protease 15 (PRSS15), also known as Lon protease, after oxidative modification.

• Partner Proteins:

  SUMO2; UBC; SUMO1; NEDD8; MDM2; ASB9; VCAM1; ITGA4; AK3; SIN3A; ACAA2; APP; ACAT1; ATXN1L; SUMO4; PSMD4; SRRM2

• Clonality:

  Polyclonal

• Type:

  Polyclonal Antibody

• Sequence:

  RYYKKHGIRWVVIGDENYGEGSSREHAALEPRHLGGRAIITKSFARIHET

• Applications:

  IHC, WB

• Purification:

  Affinity Purified

• Assay Protocol:

  Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

• Concentration:

  0.5 mg/ml

• Homology:

  Cow: 100%; Human: 100%; Pig: 100%; Rat: 100%; Yeast: 100%

• Format:

  Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

• Reconstitution:

  For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.

• Molecular Weight:

  82kDa

• Protein Length:

  780

• NCBI Gene Symbol:

  ACO2

• Host or Source:

  Rabbit

• Protein Name:

  Aconitate hydratase, mitochondrial

• Gene Name URL:

  ACO2

• CAS Number:

  9007-83-4

• Nucleotide Accession Number:

  NM_001098