APH1B antibody - C-terminal region (ARP53808_P050)

• Gene Name:

  Anterior pharynx defective 1 homolog B (C. elegans)

• Gene Aliases:

  PSFL, APH-1B, PRO1328, TAAV688

• Gene ID:

  83464

• Swiss Prot:

  Q564N3

• Accession Number:

  NP_001139118

• Reactivity:

  Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit

• Target:

  This gene encodes a multi-pass transmembrane protein that is a functional component of the gamma-secretase complex, which also contains presenilin and nicastrin. This protein represents a stabilizing cofactor for the presenilin holoprotein in the complex. The gamma-secretase complex catalyzes the cleavage of integral proteins such as notch receptors and beta-amyloid precursor protein.

• Partner Proteins:

  UBC; PSENEN; NCSTN; PSEN2; PSEN1

• Clonality:

  Polyclonal

• Type:

  Polyclonal Antibody

• Sequence:

  YYGINLASAFIILVLMGTWAFLAAGGSCRSLKLCLLCQDKNFLLYNQRSR

• Applications:

  WB

• Purification:

  Affinity Purified

• Assay Protocol:

  Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

• Concentration:

  0.5 mg/ml

• Homology:

  Cow: 77%; Dog: 85%; Guinea Pig: 92%; Horse: 77%; Human: 100%; Mouse: 92%; Rabbit: 85%; Rat: 92%

• Format:

  Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

• Reconstitution:

  For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.

• Molecular Weight:

  23kDa

• Protein Length:

  216

• NCBI Gene Symbol:

  APH1B

• Host or Source:

  Rabbit

• Protein Name:

  Gamma-secretase subunit APH-1B

• Gene Name URL:

  APH1B

• CAS Number:

  9007-83-4

• Nucleotide Accession Number:

  NM_001145646