PTP4A3 Antibody - middle region

• Gene Name:

  Protein tyrosine phosphatase type IVA, member 3

• Gene Aliases:

  PRL3, PRL-3, PRL-R

• Gene ID:

  11156

• Swiss Prot:

  O75365

• Accession Number:

  NP_116000

• Reactivity:

  Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish

• Immunogen:

  The immunogen is a synthetic peptide directed towards the middle region of human PTP4A3

• Target:

  PTP4A3 belongs to a small class of prenylated protein tyrosine phosphatases (PTPs) . PTPs are cell signaling molecules that play regulatory roles in a variety of cellular processes. This class of PTPs contains a PTP domain and a characteristic C-terminal prenylation motif. Studies of this class of PTPs in mice demonstrated that they were prenylated proteins in vivo, which suggested their association with cell plasma membrane. Overexpression of this gene in mammalian cells was reported to inhibit angiotensin-II induced cell calcium mobilization and promote cell growth.The protein encoded by this gene belongs to a small class of prenylated protein tyrosine phosphatases (PTPs) . PTPs are cell signaling molecules that play regulatory roles in a variety of cellular processes. This class of PTPs contain a PTP domain and a characteristic C-terminal prenylation motif. Studies of this class of PTPs in mice demonstrated that they were prenylated proteins in vivo, which suggested their association with cell plasma membrane. Overexpression of this gene in mammalian cells was reported to inhibit angiotensin-II induced cell calcium mobilization and promote cell growth. Two alternatively spliced variants exist.

• Partner Proteins:

  ELAVL1; FNTB; FNTA; IPO4; MMS19; NCAPG; SMAP1; SRPRB; XPO5; TTC27; FANCI; ATAD3A; TMEM33; HEATR1; DNAAF5; TNPO2; CNNM3; KIAA1279; RAB3GAP2; NUP188; KIAA0368; XPO7; GCN1L1; SMC2; LRPPRC; UBE4A; AIFM1; USO1; ABCD3; PSMD3; PRPSAP1; POLD1; HNRNPM; MSH2; MCM3

• Clonality:

  Polyclonal

• Type:

  Polyclonal Antibody

• Sequence:

  LGRAPVLVALALIESGMKYEDAIQFIRQKRRGAINSKQLTYLEKYRPKQR

• Applications:

  WB

• Purification:

  Affinity Purified

• Assay Protocol:

  Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

• Concentration:

  0.5 mg/ml

• Homology:

  Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 100%

• Format:

  Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

• Reconstitution:

  For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.

• Molecular Weight:

  19kDa

• Protein Length:

  173

• NCBI Gene Symbol:

  PTP4A3

• Host or Source:

  Rabbit

• Protein Name:

  Protein tyrosine phosphatase type IVA 3

• Gene Name URL:

  PTP4A3

• CAS Number:

  9007-83-4

• Nucleotide Accession Number:

  NM_032611