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C19orf2 Antibody - middle region

CAT: 0247-ARP50771_P050-25ULSize: 25 µLDry Ice: NoHazardous: No
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CAT#:0247-ARP50771_P050-25ULSize:25 µL
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Description
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CAS Number
9007-83-4
Gene Name
URI1, prefoldin-like chaperone
Gene Aliases
RMP, URI, NNX3, C19orf2, PPP1R19
Gene ID
8725
Swiss Prot
Q6NX55
Accession Number
NP_604431
Reactivity
Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit
Immunogen
The immunogen is a synthetic peptide directed towards the middle region of human C19orf2
Target
The function of the C19orf2 protein remains unknown.The protein encoded by this gene binds to RNA polymerase II subunit 5 (RPB5) and negatively modulates transcription through its binding to RPB5. The encoded protein seems to have inhibitory effects on various types of activated transcription, but it requires the RPB5-binding region. This protein acts as a corepressor. It is suggested that it may require signaling processes for its function or that it negatively modulates genes in the chromatin structure. Two alternatively spliced transcript variants encoding different isoforms have been described for this gene.
Partner Proteins
RPAP3; UBC; ITCH; NEDD4; ATF7; TTI1; RUVBL1; RPS6KB1; PPP1CC; HSP90AA1; APP; UXT; RPAP2; GPN1; RUVBL2; STAP1; POLR2E; URI1; DMAP1; GTF2F2
Clonality
Polyclonal
Type
Polyclonal Antibody
Sequence
NGEYVPRKSILKSRSRENSVCSDTSESSAAEFDDRRGVLRSISCEEATCS
Applications
WB
Purification
Affinity Purified
Assay Protocol
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol
Concentration
0.5 mg/ml
Homology
Cow: 93%; Dog: 86%; Guinea Pig: 93%; Horse: 86%; Human: 100%; Mouse: 79%; Rabbit: 100%; Rat: 80%
Format
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reconstitution
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
Molecular Weight
55kDa
Protein Length
495
NCBI Gene Symbol
URI1
Host or Source
Rabbit
Protein Name
Chromosome 19 open reading frame 2 EMBL AAH67259.1
Gene Name URL
URI1
Nucleotide Accession Number
NM_134447