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EIF4A1 Antibody - middle region

CAT: 0247-ARP48065_P050-25ULSize: 25 µLDry Ice: NoHazardous: No
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CAT#:0247-ARP48065_P050-25ULSize:25 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
9007-83-4
Gene Name
Eukaryotic translation initiation factor 4A1
Gene Aliases
DDX2A, EIF4A, EIF-4A, eIF4A-I, eIF-4A-I
Gene ID
1973
Swiss Prot
P60842
Accession Number
NP_001407
Reactivity
Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Sheep, Yeast, Zebrafish
Immunogen
The immunogen is a synthetic peptide directed towards the middle region of human EIF4A1
Target
EIF4A1 is an ATP-dependent RNA helicase which is a subunit of the eIF4F complex involved in cap recognition and is required for mRNA binding to ribosome. In the current model of translation initiation, eIF4A unwinds RNA secondary structures in the 5'-UTR of mRNAs which is necessary to allow efficient binding of the small ribosomal subunit, and subsequent scanning for the initiator codon.
Partner Proteins
HUWE1; UBC; FUS; SUMO2; SUMO3; STAU1; MDM2; SH3RF2; TRAP1; FBXO6; ADRB2; CD81; NPM1; VCAM1; ITGA4; FN1; ESR1; LIG4; RPLP0P6; TMEM43; NDUFB11; ZBTB43; GPRC5A; EIF4G3; EIF4H; VDAC3; UQCRFS1; SDHA; RPS26; RPL19; RPL8; RPSA; ILF2; HSP90AB1; HSPA5; EIF4G2; EIF
Clonality
Polyclonal
Type
Polyclonal Antibody
Sequence
TMPSDVLEVTKKFMRDPIRILVKKEELTLEGIRQFYINVEREEWKLDTLC
Applications
WB
Purification
Affinity Purified
Assay Protocol
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol
Concentration
0.5 mg/ml
Homology
Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Sheep: 93%; Yeast: 92%; Zebrafish: 100%
Format
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reconstitution
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
Molecular Weight
46
Protein Length
406
NCBI Gene Symbol
EIF4A1
Host or Source
Rabbit
Protein Name
Eukaryotic initiation factor 4A-I
Gene Name URL
EIF4A1
Nucleotide Accession Number
NM_001416