HSPA4 antibody - middle region (ARP46074_P050)

• Gene Name:

  Heat shock 70kDa protein 4

• Gene Aliases:

  RY, APG-2, HSPH2, hsp70, hsp70RY, HEL-S-5a, HS24/P52

• Gene ID:

  3308

• Swiss Prot:

  P34932

• Accession Number:

  NP_002145

• Reactivity:

  Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish

• Immunogen:

  The immunogen is a synthetic peptide directed towards the middle region of human HSPA4

• Target:

  HSPA4 (Hsp70) belongs to the heat shock protein 70 family. It was isolated as a putative Rictor interacting protein and interaction with membranes acts as a platform for its release into the extracellular environment during its recovery from stress. Hsp70 gene expression in Rheumatoid Arthitis-affected synovial tissue is followed by Hsp70 cell surface expression on fibroblast-like synovial cells growing from RA synovial tissue. Serum Hsp70 levels were increased in Systemic sclerosis patients, and associated with pulmonary fibrosis, skin sclerosis, renal vascular damage, oxidative stress, and inflammation.

• Partner Proteins:

  TP53; CDC25C; CDK1; AGTRAP; ERLIN2; HUWE1; Slc12a3; APPBP2; PSMD10; UBC; SUMO2; SUMO3; SIK2; MAP3K11; VHL; UIMC1; PRKCG; PRKCD; STUB1; HIF1A; ENDOG; HSPA8; TRIM5; USP19; PA2G4; WWOX; NDRG1; GZMA; GART; CRMP1; CDKN2A; CARS; PPM1G; PPAT; KARS; FAM114A1; HSP

• Clonality:

  Polyclonal

• Type:

  Polyclonal Antibody

• Sequence:

  PIKIRFQESEERPKLFEELGKQIQQYMKIISSFKNKEDQYDHLDAADMTK

• Applications:

  WB

• Purification:

  Affinity Purified

• Assay Protocol:

  Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

• Concentration:

  0.5 mg/ml

• Homology:

  Cow: 93%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 85%

• Format:

  Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

• Reconstitution:

  For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.

• Molecular Weight:

  94kDa

• Protein Length:

  840

• NCBI Gene Symbol:

  HSPA4

• Host or Source:

  Rabbit

• Protein Name:

  Heat shock 70 kDa protein 4

• Gene Name URL:

  HSPA4

• CAS Number:

  9007-83-4

• Nucleotide Accession Number:

  NM_002154