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TRIM63 Antibody - middle region

CAT: 0247-ARP43365_P050-25ULSize: 25 µLDry Ice: NoHazardous: No
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CAT#:0247-ARP43365_P050-25ULSize:25 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
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CAS Number
9007-83-4
Gene Name
Tripartite motif containing 63, E3 ubiquitin protein ligase
Gene Aliases
IRF, SMRZ, MURF1, MURF2, RNF28
Gene ID
84676
Swiss Prot
Q969Q1
Accession Number
NP_115977
Reactivity
Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit
Immunogen
The immunogen is a synthetic peptide directed towards the middle region of human TRIM63
Target
This gene encodes a member of the RING zinc finger protein family found in striated muscle and iris. The product of this gene is localized to the Z-line and M-line lattices of myofibrils, where titin's N-terminal and C-terminal regions respectively bind to the sarcomere. In vitro binding studies have shown that this protein also binds directly to titin near the region of titin containing kinase activity. Another member of this protein family binds to microtubules. Since these family members can form heterodimers, this suggests that these proteins may serve as a link between titin kinase and microtubule-dependent signal pathways in muscle.
Partner Proteins
UBE2D3; UBE2D1; UBC; TRIM63; USP37; ANKIB1; EPN1; ATXN3; EPS15; DCAF6; LMCD1; ANKRD1; NOMO1; GMEB1; NEBL; PIAS3; MRPL19; MYOT; PIAS2; SQSTM1; TCAP; PIAS1; UXT; UQCRC1; TTN; TNNI3; TNNI2; TNNI1; GFM1; TRIM55; MRPL41; MYOZ1; NEB; NDUFA1; MYBPC3; MYBPC1; EIF
Clonality
Polyclonal
Type
Polyclonal Antibody
Sequence
EQLDKSTKLVETAIQSLDEPGGATFLLTAKQLIKSIVEASKGCQLGKTEQ
Applications
WB
Purification
Affinity Purified
Assay Protocol
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol
Concentration
0.5 mg/ml
Homology
Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%
Format
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reconstitution
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
Molecular Weight
40kDa
Protein Length
353
NCBI Gene Symbol
TRIM63
Host or Source
Rabbit
Protein Name
E3 ubiquitin-protein ligase TRIM63
Gene Name URL
TRIM63
Nucleotide Accession Number
NM_032588

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