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Anti-PBEF1

CAT: 0247-ARP42255_T100Size: 100 µLDry Ice: NoHazardous: No
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CAT#:0247-ARP42255_T100Size:100 µL
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Description
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CAS Number
9007-83-4
Gene Name
Nicotinamide phosphoribosyltransferase
Gene Aliases
VF, PBEF, PBEF1, VISFATIN, 1110035O14Rik
Gene ID
10135
Swiss Prot
P43490
Accession Number
NP_005737
Reactivity
Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish
Immunogen
The immunogen is a synthetic peptide directed towards the C terminal region of human PBEF1
Target
PBEF1 catalyzes the condensation of nicotinamide with 5-phosphoribosyl-1-pyrophosphate to yield nicotinamide mononucleotide, one step in the biosynthesis of nicotinamide adenine dinucleotide. The protein is an adipokine that is localized to the bloodstream and has various functions, including the promotion of vascular smooth muscle cell maturation and inhibition of neutrophil apoptosis. It also activates insulin receptor and has insulin-mimetic effects, lowering blood glucose and improving insulin sensitivity. The protein is highly expressed in visceral fat and serum levels of the protein correlate with obesity.
Partner Proteins
UBC; NEDD8; NDRG1; CTSA; PEPD; MVD; GSR; ASS1; ANXA6; CD81; AKT2; ADORA2A; IFITM3; ND1; GGT1; FTL; CUL5; DDA1; GBAS; FANCA
Clonality
Polyclonal
Type
Polyclonal Antibody
Sequence
VTLEEGKGDLEEYGQDLLHTVFKNGKVTKSYSFDEIRKNAQLNIELEAAH
Applications
IHC, WB
Purification
Protein A purified
Assay Protocol
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol
Concentration
1.0 mg/ml
Homology
Cow: 93%; Dog: 93%; Guinea Pig: 100%; Horse: 93%; Human: 100%; Mouse: 93%; Rabbit: 93%; Rat: 100%; Zebrafish: 93%
Format
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reconstitution
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
Molecular Weight
54kDa
Protein Length
491
NCBI Gene Symbol
NAMPT
Host or Source
Rabbit
Protein Name
Nicotinamide phosphoribosyltransferase
Gene Name URL
NAMPT
Nucleotide Accession Number
NM_005746