EXOSC4

• Gene Name:

  Exosome component 4

• Gene Aliases:

  SKI6, p12A, RRP41, Ski6p, RRP41A, Rrp41p, hRrp41p

• Gene ID:

  54512

• Swiss Prot:

  Q9NPD3

• Accession Number:

  NP_061910

• Reactivity:

  Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Yeast, Zebrafish

• Immunogen:

  The immunogen is a synthetic peptide directed towards the N terminal region of human EXOSC4

• Target:

  EXOSC4 belongs to the RNase PH family. It is a component of the exosome 3'->5' exoribonuclease complex and is required for the 3' processing of the 7S pre-RNA to the mature 5.8S rRNA. It has a 3'-5' exonuclease activity.

• Partner Proteins:

  EED; TOM1; NMI; H1FX; HIST1H1E; TSEN15; GADD45GIP1; FAHD1; SMPD4; LRRC8D; EXOSC1; EXOSC3; MPZL1; SKIV2L; EXOSC10; EXOSC9; NEK1; HNRNPD; DXO; AICDA; UBC; ESR2; EXOSC5; DDX47; EXOSC2; EXOSC7; EXOSC8; PSIP1; EXOSC6; DIS3L; EXOSC4; SKIV2L2; DIS3; UPF2; MPP6

• Clonality:

  Polyclonal

• Type:

  Polyclonal Antibody

• Sequence:

  SDQGYRVDGRRAGELRKIQARMGVFAQADGSAYIEQGNTKALAVVYGPHE

• Applications:

  IHC, WB

• Purification:

  Protein A purified

• Assay Protocol:

  Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

• Concentration:

  1.0 mg/ml

• Homology:

  Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Yeast: 92%; Zebrafish: 93%

• Format:

  Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

• Reconstitution:

  For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.

• Molecular Weight:

  27kDa

• Protein Length:

  245

• NCBI Gene Symbol:

  EXOSC4

• Host or Source:

  Rabbit

• Protein Name:

  Exosome complex component RRP41

• Gene Name URL:

  EXOSC4

• Nucleotide Accession Number:

  NM_019037