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EXOSC4

CAT: 0247-ARP40935_T100Size: 100 µLDry Ice: NoHazardous: No
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CAT#:0247-ARP40935_T100Size:100 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Gene Name
Exosome component 4
Gene Aliases
SKI6, p12A, RRP41, Ski6p, RRP41A, Rrp41p, hRrp41p
Gene ID
54512
Swiss Prot
Q9NPD3
Accession Number
NP_061910
Reactivity
Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Yeast, Zebrafish
Immunogen
The immunogen is a synthetic peptide directed towards the N terminal region of human EXOSC4
Target
EXOSC4 belongs to the RNase PH family. It is a component of the exosome 3'->5' exoribonuclease complex and is required for the 3' processing of the 7S pre-RNA to the mature 5.8S rRNA. It has a 3'-5' exonuclease activity.
Partner Proteins
EED; TOM1; NMI; H1FX; HIST1H1E; TSEN15; GADD45GIP1; FAHD1; SMPD4; LRRC8D; EXOSC1; EXOSC3; MPZL1; SKIV2L; EXOSC10; EXOSC9; NEK1; HNRNPD; DXO; AICDA; UBC; ESR2; EXOSC5; DDX47; EXOSC2; EXOSC7; EXOSC8; PSIP1; EXOSC6; DIS3L; EXOSC4; SKIV2L2; DIS3; UPF2; MPP6
Clonality
Polyclonal
Type
Polyclonal Antibody
Sequence
SDQGYRVDGRRAGELRKIQARMGVFAQADGSAYIEQGNTKALAVVYGPHE
Applications
IHC, WB
Purification
Protein A purified
Assay Protocol
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol
Concentration
1.0 mg/ml
Homology
Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Yeast: 92%; Zebrafish: 93%
Format
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reconstitution
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
Molecular Weight
27kDa
Protein Length
245
NCBI Gene Symbol
EXOSC4
Host or Source
Rabbit
Protein Name
Exosome complex component RRP41
Gene Name URL
EXOSC4
Nucleotide Accession Number
NM_019037