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EIF4B Antibody - middle region

CAT: 0247-ARP40360_P050-25ULSize: 25 µLDry Ice: NoHazardous: No
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CAT#:0247-ARP40360_P050-25ULSize:25 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
9007-83-4
Gene Name
Eukaryotic translation initiation factor 4B
Gene Aliases
EIF-4B, PRO1843
Gene ID
1975
Swiss Prot
P23588
Accession Number
NP_001408
Reactivity
Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit
Immunogen
The immunogen is a synthetic peptide directed towards the middle region of human EIF4B
Target
IF4B contains 1 RRM (RNA recognition motif) domain and is required for the binding of mRNA to ribosomes. Functions of EIF4B are in close association with EEF4-F and EIF4-A. It binds near the 5'-terminal cap of mRNA in presence of EIF-4F and ATP and promotes the ATPase activity and the ATP-dependent RNA unwinding activity of both EIF4-A and EIF4-F.
Partner Proteins
UBC; ASB2; ZBTB1; SAMHD1; XPO7; SEC23A; PRMT3; CUL4B; USP11; SF1; XRCC5; OSBP; NARS; Stk11; CTNNA1; PARK2; FBXO6; PAN2; CSNK2A1; EIF4A3; YWHAE; MAGOH; SMURF1; NUP107; PHAX; SLC4A1AP; CCT6B; NUP153; POLR1C; RPL29; MYH9; EIF4G2; EIF4G1; EIF4A1; CSTF2; CUL3
Clonality
Polyclonal
Type
Polyclonal Antibody
Sequence
QTGNSSRGPGDGGNRDHWKESDRKDGKKDQDSRSAPEPKKPEENPASKFS
Applications
WB
Purification
Affinity Purified
Assay Protocol
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol
Concentration
0.5 mg/ml
Homology
Cow: 86%; Dog: 93%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 86%; Rabbit: 92%; Rat: 100%
Format
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reconstitution
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
Molecular Weight
69kDa
Protein Length
611
NCBI Gene Symbol
EIF4B
Host or Source
Rabbit
Protein Name
Eukaryotic translation initiation factor 4B
Gene Name URL
EIF4B
Nucleotide Accession Number
NM_001417

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