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CBFA2T2 Antibody - middle region

CAT: 0247-ARP38559_P050-25ULSize: 25 µLDry Ice: NoHazardous: No
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CAT#:0247-ARP38559_P050-25ULSize:25 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
9007-83-4
Gene Name
Core-binding factor, runt domain, alpha subunit 2; translocated to, 2
Gene Aliases
EHT, p85, MTGR1, ZMYND3
Gene ID
9139
Swiss Prot
O43439
Accession Number
NP_005084
Reactivity
Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit
Immunogen
The immunogen is a synthetic peptide directed towards the middle region of human CBFA2T2
Target
In acute myeloid leukemia, especially in the M2 subtype, the t (8;21) (q22; q22) translocation is one of the most frequent karyotypic abnormalities. The translocation produces a chimeric gene made up of the 5'-region of the RUNX1 (AML1) gene fused to the 3'-
Partner Proteins
PRDM14; PDP1; CBFA2T2; TCP1; MDFI; RUNX1T1; LBP; APP; ATXN1L; ATN1; RERE; RUNX1; SIN3A; NCOR1; HDAC3; FBXL19; TAL2; NEUROG1; ID3; GTF2E1; WDYHV1; CBFA2T3; NCOR2; CBFB; TAL1
Clonality
Polyclonal
Type
Polyclonal Antibody
Sequence
GQGRPLLPVGRGSSARSADCSVPSPALDKTSATTSRSSTPASVTAIDTNG
Applications
WB
Purification
Affinity Purified
Assay Protocol
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol
Concentration
0.5 mg/ml
Homology
Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 93%; Rabbit: 93%; Rat: 100%
Format
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reconstitution
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
Molecular Weight
67kDa
Protein Length
604
NCBI Gene Symbol
CBFA2T2
Host or Source
Rabbit
Protein Name
Protein CBFA2T2
Gene Name URL
CBFA2T2
Nucleotide Accession Number
NM_013277

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