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DHX8 Antibody - N-terminal region

CAT: 0247-ARP36380_P050-25ULSize: 25 µLDry Ice: NoHazardous: No
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CAT#:0247-ARP36380_P050-25ULSize:25 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
9007-83-4
Gene Name
DEAH (Asp-Glu-Ala-His) box polypeptide 8
Gene Aliases
DDX8, Dhr2, HRH1, PRP22, PRPF22
Gene ID
1659
Swiss Prot
Q14562
Accession Number
NP_004932
Reactivity
Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit
Immunogen
The immunogen is a synthetic peptide directed towards the N terminal region of human DHX8
Target
DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. This gene encodes a DEAD box protein, which is highly homologous to yeast Prp22. This protein facilitates nuclear export of spliced mRNA by releasing the RNA from the spliceosome.
Partner Proteins
NUDCD1; UBC; LIN28A; XRN2; SRPK2; SRPK1; BAG3; PRPF38A; NKAP; ISY1; PRPF40A; ZCCHC10; RBMX2; SAP30BP; CHERP; RBM7; THOC1; MFAP1; DHX8; NOTCH1; KANSL1; PHF5A; MYPN; POLR1B; CRNKL1; TAF9; SMAD3; SMAD2; CAND1; CUL3; SIRT7; USP12
Clonality
Polyclonal
Type
Polyclonal Antibody
Sequence
VKNGAEFTDSLISNLLRLIQTMRPPAKPSTSKDPVVKPKTEKEKLKELFP
Applications
WB
Purification
Affinity Purified
Assay Protocol
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol
Concentration
0.5 mg/ml
Homology
Cow: 100%; Dog: 88%; Guinea Pig: 100%; Horse: 93%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 93%
Format
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reconstitution
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
Molecular Weight
139kDa
Protein Length
1220
NCBI Gene Symbol
DHX8
Host or Source
Rabbit
Protein Name
ATP-dependent RNA helicase DHX8
Gene Name URL
DHX8
Nucleotide Accession Number
NM_004941

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