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TOP5300

CAT: 0804-HY-160856Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-160856Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
TOP5300 is an orally active follicle-stimulating hormone receptor allosteric agonist. TOP5300 can induce the production of testosterone in stromal cells and promote follicular genesis and superovulation in rats[1].
CAS Number
1848981-48-5
Product Name Alternative
TOP05300
UNSPSC
12352005
Target
Estrogen Receptor/ERR
Type
Reference compound
Related Pathways
Vitamin D Related/Nuclear Receptor
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Endocrinology
Assay Protocol
https://www.medchemexpress.com/top5300.html
Solubility
10 mM in DMSO
Smiles
O=C(N(C(C)(C)C)C)C1=NN(C2=C1COC3=C2C=C(C4=CN(CCO)N=C4)C(OC)=C3)C5=CC(Cl)=CC(Cl)=C5
Molecular Formula
C28H29Cl2N5O4
Molecular Weight
570.47
References & Citations
[1]Nataraja S, et al. Discovery and Preclinical Development of Orally Active Small Molecules that Exhibit Highly Selective Follicle Stimulating Hormone Receptor Agonism. Front Pharmacol. 2021 Jan 14;11:602593.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

Alternative Products

CatalogName
T209867-01TOP5300

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