PTGER3 Antibody - middle region

• Gene Name:

  Prostaglandin E receptor 3 (subtype EP3)

• Gene Aliases:

  EP3, EP3e, EP3-I, EP3-II, EP3-IV, EP3-VI, PGE2-R, EP3-III, lnc003875

• Gene ID:

  5733

• Swiss Prot:

  P43115

• Accession Number:

  NP_942012

• Reactivity:

  Human, Horse, Rabbit

• Immunogen:

  The immunogen is a synthetic peptide directed towards the middle region of human PTGER3

• Target:

  PTGER3 is the receptor for prostaglandin E2 (PGE2) ; the EP3 receptor may be involved in inhibition of gastric acid secretion, modulation of neurotransmitter release in central and peripheral neurons, inhibition of sodium and water reabsorption in kidney tubulus and contraction in uterine smooth muscle. The activity of this receptor can couple to both the inhibition of adenylate cyclase mediated by G-I proteins, and to an elevation of intracellular calcium. The various isoforms have identical ligand binding properties but can interact with different second messenger systems.The protein encoded by this gene is a member of the G-protein coupled receptor family. This protein is one of four receptors identified for prostaglandin E2 (PGE2) . This receptor may have many biological functions, which involve digestion, nervous system, kidney reabsorption, and uterine contraction activities. Studies of the mouse counterpart suggest that this receptor may also mediate adrenocorticotropic hormone response as well as fever generation in response to exogenous and endogenous stimuli. Multiple alternatively spliced transcript variants encoding eight distinct isoforms have been reported.

• Partner Proteins:

  NOTCH2NL; INCA1; KRTAP10-3; KRTAP10-8; KRTAP10-9; KRTAP10-7; TRIM42; MGAT5B; KRT40; CCDC33; ADAMTSL4; EFEMP2; RGS17; SPRY2; KRT38; RGS20; TCF4; REL; MEOX2; KRT31; CDA; GHRL; MKLN1; PTGER1

• Clonality:

  Polyclonal

• Type:

  Polyclonal Antibody

• Sequence:

  ILDPWVYLLLRKILLRKFCQIRYHTNNYASSSTSLPCQCSSTLMWSDHLE

• Applications:

  WB

• Purification:

  Affinity Purified

• Assay Protocol:

  Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

• Concentration:

  0.5 mg/ml

• Homology:

  Horse: 100%; Human: 100%; Rabbit: 100%

• Format:

  Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

• Reconstitution:

  For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.

• Molecular Weight:

  43kDa

• Protein Length:

  390

• NCBI Gene Symbol:

  PTGER3

• Host or Source:

  Rabbit

• Protein Name:

  Prostaglandin E2 receptor EP3 subtype

• Gene Name URL:

  PTGER3

• CAS Number:

  9007-83-4

• Nucleotide Accession Number:

  NM_198719