PAX6 antibody - N-terminal region (ARP32741_P050)

• Gene Name:

  Paired box 6

• Gene Aliases:

  AN, AN1, AN2, FVH1, MGDA, WAGR, ASGD5, D11S812E

• Gene ID:

  5080

• Swiss Prot:

  P26367-2

• Accession Number:

  NP_001595

• Reactivity:

  Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish

• Immunogen:

  The immunogen is a synthetic peptide directed towards the N terminal region of human PAX6

• Target:

  PAX6 is one of many human homologues of the Drosophila melanogaster gene prd. In addition to the hallmark feature of this gene family, a conserved paired box domain, the encoded protein also contains a homeo box domain. Both domains are known to bind DNA, This gene encodes paired box gene 6, one of many human homologues of the Drosophila melanogaster gene prd. In addition to the hallmark feature of this gene family, a conserved paired box domain, the encoded protein also contains a homeo box domain. Both domains are known to bind DNA, and function as regulators of gene transcription. This gene is expressed in the developing nervous system, and in developing eyes. Mutations in this gene are known to cause aniridia as well as Peter's anomaly, both ocular diseases.

• Partner Proteins:

  IPO13; Dlg4; NKIRAS2; Cacnb3; Pax6; Diap1; SMAD5; SMAD4; SMAD3; SMAD1; AR; HIPK2; SUMO1; SMARCA4; TP73; SHANK3; PBX1; VSX2; EN1; TRIM11; HOMER3; SIX3; INADL; EP300; SOX10; RGS3; DIAPH1; MAFG; RAX; DYNLL1; DLG1; CDX2; TBP; SOX3; MITF; HOXB1; SOX2; LHX2; TA

• Clonality:

  Polyclonal

• Type:

  Polyclonal Antibody

• Sequence:

  GRPLPDSTRQKIVELAHSGARPCDISRILQTHADAKVQVLDNQNVSNGCV

• Applications:

  WB

• Purification:

  Affinity Purified

• Assay Protocol:

  Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

• Concentration:

  0.5 mg/ml

• Homology:

  Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 100%

• Format:

  Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

• Reconstitution:

  For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.

• Molecular Weight:

  48kDa

• Protein Length:

  436

• NCBI Gene Symbol:

  PAX6

• Host or Source:

  Rabbit

• Protein Name:

  Paired box protein Pax-6

• Gene Name URL:

  PAX6

• CAS Number:

  9007-83-4

• Nucleotide Accession Number:

  NM_001604