RegisterLogin

ERBB3 Antibody

CAT: 247-ARP30252_P050-25ULSize: 25 µLDry Ice: NoHazardous: No
25 µLSelected
PRICE
AVAILABILITY
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Product image 1
1 / 1
CAS Number
9007-83-4
Gene Name
V-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian)
Gene Aliases
HER3, FERLK, LCCS2, ErbB-3, c-erbB3, erbB3-S, MDA-BF-1, c-erbB-3, p180-ErbB3, p45-sErbB3, p85-sErbB3
Gene ID
2065
Swiss Prot
P21860
Accession Number
NP_001973
Reactivity
Human, Mouse, Rat, Cow, Guinea Pig, Horse
Immunogen
The immunogen is a synthetic peptide directed towards the following sequence GLLFSLARGSEVGNSQAVCPGTLNGLSVTGDAENQYQTLYKLYERCEVVM
Target
This gene encodes a member of the epidermal growth factor receptor (EGFR) family of receptor tyrosine kinases. This membrane-bound protein has a neuregulin binding domain but not an active kinase domain. It therefore can bind this ligand but not convey the signal into the cell through protein phosphorylation. However, it does form heterodimers with other EGF receptor family members which do have kinase activity. Heterodimerization leads to the activation of pathways which lead to cell proliferation or differentiation. Amplification of this gene and/or overexpression of its protein have been reported in numerous cancers, including prostate, bladder, and breast tumors. Alternate transcriptional splice variants encoding different isoforms have been characterized. One isoform lacks the intermembrane region and is secreted outside the cell. This form acts to modulate the activity of the membrane-bound form. Additional splice variants have also been reported, but they have not been thoroughly characterized.
Partner Proteins
PA2G4; UBC; NEDD4; JAK3; JAK2; ITK; HSP90AA1; HCK; GRB7; FGFR1; FER; PIK3R2; PIK3R1; NCK1; SH2D1A; TNS4; TNS3; SHC3; DAPP1; TENC1; VAV3; SH2B3; RIN1; PIK3R3; NCK2; BCAR3; ZAP70; VAV2; VAV1; TXK; SYK; SRC; SHC1; RASA1; PTK6; PLCG1; DAB1; CRKL; CRK; CHN2; A
Clonality
Polyclonal
Type
Polyclonal Antibody
Sequence
GLLFSLARGSEVGNSQAVCPGTLNGLSVTGDAENQYQTLYKLYERCEVVM
Applications
IHC
Purification
Affinity Purified
Assay Protocol
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol
Concentration
0.5 mg/ml
Homology
Cow: 92%; Guinea Pig: 100%; Horse: 92%; Human: 100%; Mouse: 92%; Rat: 92%
Format
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reconstitution
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
Molecular Weight
148 kDa
Protein Length
1342
NCBI Gene Symbol
ERBB3
Host or Source
Rabbit
Protein Name
Receptor tyrosine-protein kinase erbB-3
Gene Name URL
ERBB3
Nucleotide Accession Number
NM_001005915

Related Products

CatalogName
OPPA01566-5UGErbB3 Protein
OACA12812-100ULERBB3 Recombinant Antibody [6F6] (OACA12812)
OCOA16793-20UGERBB3 Protein Lysate
OPCD02968-10UGERBB3 Recombinant Protein
OCOA00649-20UGERBB3 Protein Lysate
OPCD02968-50UGERBB3 Recombinant Protein
OCOA17676-20UGERBB3 Protein Lysate
OPCD02967-200UGERBB3 Recombinant Protein
OPCD02967-50UGERBB3 Recombinant Protein
OPCD02967-10UGERBB3 Recombinant Protein

Alternative Products

CatalogName
MBS8516061-01ERBB3 Antibody
MBS8502432-01ERBB3 Antibody
MBS7122484-01ERBB3 Antibody
MBS7123514-01ERBB3 Antibody
MBS7123515-01ERBB3 Antibody
MBS7116308-01ERBB3 Antibody
MBS9606804-01ERBB3 Antibody
F53392-0.08MLErbb3 Antibody
MBS2519046-01ERBB3 Antibody
MBS3200202-01ERBB3 Antibody

Popular Products