Thapsigargin

• Target:

  Calcium Channel|||Apoptosis|||SARS-CoV

• Related Pathways:

  Membrane transporter/Ion channel|||Apoptosis|||Metabolism|||Microbiology/Virology

• Purity:

  0.993

• Bioactivity:

  Thapsigargin is a natural product, an inhibitor of sarcoplasmic/endoplasmic reticulum Ca2+ ATPase (SERCA) and an endoplasmic reticulum stress inducer. Thapsigargin increases cytoplasmic calcium concentration by blocking the ability of cells to pump calcium into the sarcoplasmic and endoplasmic reticulum.

• Smiles:

  CCCCCCCC (=O) O[C@@H]1[C@@H] (OC (=O) C (C) =CC) C (C) =C2[C@@H]3OC (=O) [C@@] (C) (O) [C@@]3 (O) [C@H] (C[C@] (C) (OC (C) =O) [C@@H]12) OC (=O) CCC

• Molecular Formula:

  C34H50O12

• Molecular Weight:

  650.75

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  67526-95-8