Pralsetinib

• Target :

  C-RET

• Related Pathways :

  Apoptosis|||Tyrosine Kinase/Adaptors

• Purity :

  0.998

• Bioactivity :

  Pralsetinib (Blu667) (BLU-667) is a highly potent, selective RET inhibitor (IC50s: 0.4, 0.3, 0.4, 0.4, and 0.4 nM for WT RET, RET mutants V804L, V804M, M918T and CCDC6-RET fusion) .

• Smiles :

  CO[C@]1(CC[C@@H](CC1)c1nc(C)cc(Nc2cc(C)[nH]n2)n1)C(=O)N[C@@H](C)c1ccc(nc1)-n1cc(F)cn1

• Molecular Formula :

  C27H32FN9O2

• Molecular Weight :

  533.6

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  2097132-94-8