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INCB3344

CAT: 0931-TQ0103-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0931-TQ0103-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
1262238-11-8
Target
CCR
Related Pathways
Immunology/Inflammation, GPCR/G Protein, Microbiology/Virology
Purity
0.982
Bioactivity
INCB3344 is an effective, specific and orally bioavailable CCR2 antagonist with IC50 values of 9.5 nM (mCCR2) and 5.1 nM (hCCR2) in binding antagonism and 7.8 nM (mCCR2) and in 3.8 nM (hCCR2) antagonism of chemotaxis activity.
Smiles
[H][C@@]1(CC[C@](O)(CC1)c1ccc2OCOc2c1)N1C[C@H](NC(=O)CNC(=O)c2cccc(c2)C(F)(F)F)[C@H](C1)OCC
Molecular Formula
C29H34F3N3O6
Molecular Weight
577.59
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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A11465-100INCB3344 100mg
A11465-5INCB3344 5mg
A11465-1INCB3344 1mg
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