INCB3344

• Target :

  CCR

• Related Pathways :

  Immunology/Inflammation|||GPCR/G Protein|||Microbiology/Virology

• Purity :

  0.982

• Bioactivity :

  INCB3344 is an effective, specific and orally bioavailable CCR2 antagonist with IC50 values of 9.5 nM (mCCR2) and 5.1 nM (hCCR2) in binding antagonism and 7.8 nM (mCCR2) and in 3.8 nM (hCCR2) antagonism of chemotaxis activity.

• Smiles :

  [H][C@@]1(CC[C@](O)(CC1)c1ccc2OCOc2c1)N1C[C@H](NC(=O)CNC(=O)c2cccc(c2)C(F)(F)F)[C@H](C1)OCC

• Molecular Formula :

  C29H34F3N3O6

• Molecular Weight :

  577.59

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  1262238-11-8