KO-947

CAT: 0931-TQ0005-06Size: 100 mgDry Ice: NoHazardous: No

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CAT#:0931-TQ0005-06Size:100 mg

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24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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CAS Number

1695533-89-1

Target

ERK

Related Pathways

MAPK

Purity

0.9784

Bioactivity

KO-947 is a potent and specific ERK1/2 kinase inhibitor.

Smiles

O=C1Nc2cc3[nH]nc(-c4ccncc4)c3cc2CN1Cc1ccccc1

Molecular Formula

C21H17N5O

Molecular Weight

355.39

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Chemical Information

Ko-947

CAS Number	1695533-89-1
PubChem CID	136653617
IUPAC Name	6-benzyl-3-pyridin-4-yl-5,8-dihydro-1H-pyrazolo[4,5-g]quinazolin-7-one
Molecular Formula	C21H17N5O
Molecular Weight	355.4
XLogP	2.4
Topological Polar Surface Area	73.9
Hydrogen Bond Donor Count	2
Hydrogen Bond Acceptor Count	3
Rotatable Bond Count	3
Heavy Atom Count	27
Formal Charge	0
Complexity	531

SMILES

C1C2=CC3=C(C=C2NC(=O)N1CC4=CC=CC=C4)NN=C3C5=CC=NC=C5

InChI

InChI=1S/C21H17N5O/c27-21-23-18-11-19-17(20(25-24-19)15-6-8-22-9-7-15)10-16(18)13-26(21)12-14-4-2-1-3-5-14/h1-11H,12-13H2,(H,23,27)(H,24,25)

InChIKey

ODIUJYZERXVGEI-UHFFFAOYSA-N

Chemical Structure

2D Structure

CAS: 1695533-89-1

CID: 136653617

Formula: C21H17N5O

MW: 355.4

Interactive 3D Structure

Loading 3D structure...

View on PubChem Raw 3D data

Computed Properties

Property	Value
Molecular Weight	355.4
XLogP3	2.4
Hydrogen Bond Donor Count	2
Hydrogen Bond Acceptor Count	3
Rotatable Bond Count	3
Exact Mass	355.14331018
Monoisotopic Mass	355.14331018
Topological Polar Surface Area	73.9 Å²
Heavy Atom Count	27
Formal Charge	0
Complexity	531
Isotope Atom Count	0
Defined Atom Stereocenter Count	0
Undefined Atom Stereocenter Count	0
Defined Bond Stereocenter Count	0
Undefined Bond Stereocenter Count	0
Covalently-Bonded Unit Count	1
Compound Is Canonicalized	Yes

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Alternative Products

Catalog	Name
BA6434-100	KO-947
A19903-10	KO-947 10mg
A19903-5	KO-947 5mg
A19903-1	KO-947 1mg
A19903-100	KO-947 100mg
A19903-50	KO-947 50mg
A19903-25	KO-947 25mg
GTR19160639-01	CI-947

KO-947

Chemical Information

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