Products for Research Use Only
RegisterLogin

Balixafortide

CAT: 0931-TP2141L-01Size: 100 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0931-TP2141L-01Size:100 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
CAS Number
1051366-32-5
Target
CXCR, Arrestin
Related Pathways
Immunology/Inflammation, GPCR/G Protein, Autophagy
Bioactivity
Balixafortide (POL6326) is a potent, selective, and well-tolerated peptidic CXCR4 antagonist with an IC50 < 10 nM, and also acts as a potent hematopoietic stem and progenitor cell (HSPC) mobilizing agent. It demonstrates anti-cancer effects[1][2], blocks β-arrestin recruitment and calcium flux with IC50s < 10 nM, and is 1000-fold more selective for CXCR4 than a large panel of receptors, including CXCR7.
Smiles
[H][C@]12CCCN1C(=O)[C@H](C)NC(=O)[C@H](CO)NC(=O)[C@@H]1CSSC[C@H](NC(=O)[C@H](Cc3ccc(O)cc3)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CCN)NC2=O)C(=O)N[C@@H](Cc2ccc(O)cc2)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCCCN)C(=O)N2CCC[C@]2([H])C(=O)N2CCC[C@@]2([H])C(=O)N[C@@H](Cc2ccc(O)cc2)C(=O)N[C@@H](Cc2cnc[nH]2)C(=O)N[C@@H](C)C(=O)N1
Molecular Formula
C84H118N24O21S2
Molecular Weight
1864.14
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

Alternative Products

CatalogName
HY-P1682-01Balixafortide
S9725-01Balixafortide (POL6326)
HY-P1682A-01Balixafortide (TFA)
MBS5764132Balixafortide TFA
A24310-5Balixafortide (POL6326) 5mg
A24310-100Balixafortide (POL6326) 100mg
A24310-10Balixafortide (POL6326) 10mg
205864Balixafortide TFA salt
A24310-50Balixafortide (POL6326) 50mg
GTR19029089-01Balixafortide TFA (1051366-32-5 free base)

Popular Products