C-JUN peptide

• Target :

  JNK|||Apoptosis

• Related Pathways :

  MAPK|||Apoptosis

• Bioactivity :

  Peptide comprising residues 33 - 57 of the JNK binding (?) domain of human c-Jun. Disrupts JNK/c-Jun interaction leading to inhibition of serum-induced c-Jun phosphorylation, up-regulation of p21cip/waf and modulation of inflammatory gene expression. Specifically induces apoptosis in HeLa tumor cells.

• Smiles :

  C([C@@H](NC([C@@H](NC([C@@H](NC(CNC([C@@H](NC(=O)[C@H]1N(C([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@H]([C@H](CC)C)N)=O)CC(C)C)=O)CCCCN)=O)CCC(N)=O)=O)CO)=O)CCSC)=O)[C@@H](C)O)=O)CC(C)C)=O)CC(N)=O)=O)CC(C)C)=O)C)=O)CC(O)=O)=O)CCC1)C(C)C)=O)=O)CO)=O)CC(C)C)=O)CCCCN)(=O)N2[C@H](C(N[C@@H](CC3=CN=CN3)C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@@H](CC(N)=O)C(O)=O)=O)CCCCN)=O)C)=O)CCCNC(=N)N)=O)CC(C)C)=O)=O)CCC2

• Molecular Formula :

  C121H210N36O34S

• Molecular Weight :

  2743.55

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  610273-01-3