Echistatin

• Target :

  Integrin

• Related Pathways :

  Cytoskeletal Signaling

• Bioactivity :

  Potent irreversible ?V?3 integrin antagonist (Ki = 0.27 nM) . Disrupts attachment of osteoclasts to bone and inhibits bone reabsorption (IC50 = 0.1 nM) . Prevents ADP-induced platelet aggregation via inhibition of glycoprotein IIb/IIIa (GpIIb/IIIa, ?IIb?3) receptors (IC50 = 30 nM) in vitro.

• Molecular Formula :

  C217H341N71O74S9

• Molecular Weight :

  5417.1

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  154303-05-6